ArticleHorticulture research2021
SlGRAS4 accelerates fruit ripening by regulating ethylene biosynthesis genes and SlMADS1 in tomato.
Article in Horticulture research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 74 citations in OpenAlex.
- Cultivar-Dependent Biosynthesis, Sustainable Recovery, and Industrial Applications of Tomato-Derived Carotenoids.Plants (Basel, Switzerland) · 2026Review
- Temperature Dominates Light in Regulating Lycopene During a Critical Period in Postharvest Tomato Fruit.International journal of molecular sciences · 2026Article
- OfERF106-OfACS2 regulatory module helps accelerate the aging process of Osmanthus fragrans petals.Plant cell reports · 2026Article
- The carotenoids metabolism during tomato fruit ripening: insights into multi-level regulatory network.BMC plant biology · 2026Review
- Article
- Transcriptional control of tomato fruit development and ripening.Journal of experimental botany · 2025Review
- Tomato ripening regulator SlSAD8 disturbs nuclear gene transcription and chloroplast-associated protein degradation.Nature plants · 2025Article
- Genome-Wide Identification and Expression Analysis of 1-Aminocyclopropane-1-Carboxylate Synthase (ACS) Gene Family inInternational journal of molecular sciences · 2025Article
- Autosuppression of MdNAC18.1 endowed by a 61-bp promoter fragment duplication delays maturity date in apple.Plant biotechnology journal · 2025Article
- Identification and characterization of GRAS genes in passion fruit (Passiflora edulis Sims) revealed their roles in development regulation and stress response.Plant cell reports · 2025Article
- The GRAS transcription factor PtrPAT1 ofHorticulture research · 2025Article
- Evolution and Function of MADS-Box Transcription Factors in Plants.International journal of molecular sciences · 2024Review
- EjWRKY6 Is Involved in the ABA-Induced Carotenoid Biosynthesis in Loquat Fruit during Ripening.Foods (Basel, Switzerland) · 2024Article
- Article
- And yet another transcription factor-the complex world of fruit ripening.Plant physiology · 2024Article
- Transcriptional regulation of tomato fruit ripening.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- The miR156/SPL12 module orchestrates fruit colour change through directly regulating ethylene production pathway in blueberry.Plant biotechnology journal · 2024Article
- Recent Advances in Studying the Regulation of Fruit Ripening in Tomato Using Genetic Engineering Approaches.International journal of molecular sciences · 2024Review
- Network of GRAS transcription factors in plant development, fruit ripening and stress responses.Horticulture research · 2023Article
- Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
GRAS proteins are plant-specific transcription factors that play crucial roles in plant development and stress responses. However, their involvement in the ripening of economically important fruits and their transcriptional regulatory mechanisms remain largely unclear. Here, we demonstrated that SlGRAS4, encoding a transcription factor of the GRAS family, was induced by the tomato ripening process and regulated by ethylene. Overexpression of SlGRAS4 accelerated fruit ripening, increased the total carotenoid content and increased PSY1 expression in SlGRAS4-OE fruit compared to wild-type fruit. The expression levels of key ethylene biosynthesis genes (SlACS2, SlACS4, SlACO1, and SlACO3) and crucial ripening regulators (RIN and NOR) were increased in SlGRAS4-OE fruit. The negative regulator of tomato fruit ripening, SlMADS1, was repressed in OE fruit. Exogenous ethylene and 1-MCP treatment revealed that more endogenous ethylene was derived in SlGRAS4-OE fruit. More obvious phenotypes were observed in OE seedlings after ACC treatment. Yeast one-hybrid and dual-luciferase assays confirmed that SlGRAS4 can directly bind SlACO1 and SlACO3 promoters to activate their transcription, and SlGRAS4 can also directly repress SlMADS1 expression. Our study identified that SlGRAS4 acts as a new regulator of fruit ripening by regulating ethylene biosynthesis genes in a direct manner. This provides new knowledge of GRAS transcription factors involved in regulating fruit ripening.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.