ArticleProceedings of the National Academy of Sciences of the United States of America2021
Discrimination and anxiety: Using multiple polygenic scores to control for genetic liability.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Associations among discrimination, genetic susceptibility to inflammation, and C-reactive protein.Brain, behavior, & immunity - health · 2026Article
- Observational epidemiological studies can mitigate genetic confounding with a genetic relatedness matrix.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Measuring early experiences: Challenges and future directions.Developmental cognitive neuroscience · 2025Review
- Understanding Links between Race/Ethnicity and Health: Does Participation in the Musical Arts Matter?Psychology of aesthetics, creativity, and the arts · 2025Article
- Predictors of vaccine uptake during a pandemic: The interplay of lifetime discrimination, educational attainment, and family support.Journal of health psychology · 2025Article
- Coping with ethnic-racial discrimination: Protective-reactive effects of shift-and-persist coping on internalizing symptoms among Black American adolescents.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2024Article
- Controlling for polygenic genetic confounding in epidemiologic association studies.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Variety in Pleasant Activities is Associated with Improved Mental Health: Evidence from Two National Samples of U.S. Adults.Affective science · 2024Article
- Controlling for polygenic genetic confounding in epidemiologic association studies.bioRxiv : the preprint server for biology · 2024Article
- Article
- A cross-sectional study on resilience, anxiety, depression, and psychoactive substance use among heterosexual and sexual minority adolescents in Nigeria.BMC public health · 2023Article
- Perceived discrimination, anxiety and mood disorders among university students during the COVID-19 era: evidence from a cross-sectional survey in a Ghanaian public university.Frontiers in psychology · 2023Article
- Examining the Reciprocity Between Perceived Discrimination and Health: A Longitudinal Perspective.Population research and policy review · 2022Article
- Racism in oral healthcare settings: Implications for dental care-related fear/anxiety and utilization among Black/African American women in Appalachia.Journal of public health dentistry · 2022Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
An established body of research indicates that discrimination is associated with increased symptoms of anxiety and negative affect. However, the association cannot be interpreted unambiguously as an exposure effect because a common set of genetic factors can simultaneously contribute to increased liability for symptoms of anxiety, negative affect, and the perception of discrimination. The present study elucidates the association between discrimination and anxiety/negative affect by implementing strict genetic controls in a large sample of adults. We used data from the biomarker project of the Study of Midlife Development in the United States (MIDUS), a national probability sample of noninstitutionalized, English-speaking respondents aged 25 to 74 y. Participants who consented to provide genetic data were biologically unrelated and of European ancestry as determined by genotype principal components analysis (
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