Evidence map›Paper›PMID 33384142›Full record

ReviewBiochemical and biophysical research communications2021

Comprehensive analysis of COVID-19 during pregnancy.

Kathryn M Moore, Mehul S Suthar

Open access · greenAbstract readReview
In one paragraph

Review in Biochemical and biophysical research communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.

  1. Pooled it
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  12. SARS-CoV-2 neutralizing antibody titers in maternal blood, umbilical cord blood, and breast milk.Journal of perinatology : official journal of the California Perinatal Association · 2024
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kathryn M MooreCenter for Childhood Infections and Vaccines, Children's Healthcare of Atlanta and Emory University Department of Pediatrics, Atlanta, GA, 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, 30329, USA; Yerkes National Primate Research Center, Atlanta, GA, 30329, USA.
Mehul S SutharCenter for Childhood Infections and Vaccines, Children's Healthcare of Atlanta and Emory University Department of Pediatrics, Atlanta, GA, 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, 30329, USA; Yerkes National Primate Research Center, Atlanta, GA, 30329, USA. Electronic address: mehul.s.suthar@emory.edu.
Emory University · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
VACCINE INDUCED IMMUNITY IN THE YOUNG AND AGEDU19AI057266 · NIAID · EMORY UNIVERSITY · PI Rafi Ahmed · 2003 to 2026
$81.7M
Systems Biological Analysis of Innate and Adaptive Responses to VaccinationU19AI090023 · NIAID · EMORY UNIVERSITY · PI AHMED, RAFI, LI, SHUZHAO · 2010 to 2021
$45.0M
Host dependence of influenza A virus spatio-temporal dynamicsR01AI127799 · NIAID · EMORY UNIVERSITY · PI Anice C Lowen · 2017 to 2026
$4.5M
Understanding the mechanisms of antibody-mediated transcytosis of ZIKV within the placentaR01AI149486 · NIAID · EMORY UNIVERSITY · PI SUTHAR, MEHUL SHAMAL, WRAMMERT, JENS PETER · 2020 to 2024
$3.8M
MVA Prime/Novel Trimeric Cyclically Permuted Envelope Protein Boost Vaccines for HIVR01AI148378 · NIAID · EMORY UNIVERSITY · PI AMARA, RAMA RAO · 2019 to 2022
$3.7M
Determining how macrophages regulate immunity to Zika virus infection at the maternal-fetal interfaceU01AI131566 · NIAID · EMORY UNIVERSITY · PI CHAKRABORTY, RANA, SUTHAR, MEHUL SHAMAL · 2017 to 2021
$2.3M
NIAID NIH HHS R01 AI127799NIAID NIH HHS R01 AI148378NIAID NIH HHS R01 AI149486NIAID NIH HHS U01 AI131566NIAID NIH HHS U19 AI057266NIAID NIH HHS U19 AI090023NIH HHS P51 OD011132
6 · The paper itself

Abstract

The COVID-19 pandemic resulting from the emergence of the coronavirus SARS-CoV-2 remains a major global health concern. Pregnant individuals are more likely to develop severe COVID-19 and a number of pregnancy complications have been observed in COVID-19 patients. To date, little is known about the impact of COVID-19 on pregnancy. In this review, we examine key aspects of pregnancy that may be impacted by COVID-19 and summarize the current literature on SARS-CoV-2 infection of the placenta and in utero vertical transmission. Furthermore, we highlight recent studies exploring the role of the maternal antibody response to SARS-CoV-2 during pregnancy and the passive transfer of maternal antibodies from mothers with COVID-19 to fetus.

Indexed as

Infectious Disease Transmission, VerticalAntibodies, ViralCOVID-19FemaleHumansMaternal-Fetal ExchangePlacentaPregnancyPregnancy Complications, InfectiousSARS-CoV-2UterusAntibodies, ViralAntibody responseCOVID-19PlacentaPregnancySARS-CoV-2Vertical transmission

Identifiers

PMID33384142
PMCPMC7759124
OpenAlexW3115660724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.