ArticleArthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association2021
Editorial Commentary: Discovery: Progenitor Cells and Endothelial Cells Are Found in the White-White Zone of the Meniscus, But This Does Not Mean That These Tears Heal or Should Be Repaired.
Article in Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Self-assembled meniscus-specific ECM membrane promotes cell migration and vascular ingrowth for meniscus repair and reconstruction.Journal of orthopaedic translation · 2026Article
- Three-Dimensional Imaging and Quantitative Analysis of Blood Vessel Distribution in The Meniscus of Transgenic Mouse after Tissue Clearing.Cell journal · 2023Article
Corrections and comments
- Comment on
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More than 35 years ago, the concept of vascular zones of the meniscus was introduced. It has been shown that blood supply is limited to the peripheral 25% of the lateral and 30% of the medial meniscus. This obviously has repercussions with regard to the healing potential of meniscus tears, whether repaired or not. In general, tears that extend into the white-white zone, such as flaps, cleavage tears, and radial tears, are deemed irreparable. However, several recent reports have suggested that radial tears in the white-white zone, when repaired, heal and have good clinical outcomes. Now progenitor mesenchymal cells have been identified in the white-white zones, confirming the potential of the meniscus to heal. However, blood supply was demonstrated only by indirect signs such as the presence of endothelial cells and the presence of endothelial surface markers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.