ReviewJournal of clinical medicine2020
End-of-Life Care Preferences of Older Patients with Multimorbidity: A Mixed Methods Systematic Review.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Longing for continuity: A systematic review and thematic synthesis of qualitative research on the experience of older people living with chronic illness towards the end of life.Social science & medicine (1982) · 2026Pooled it
- Contexts and mechanisms relevant to General Practitioner (GP) based interventions to reduce adverse drug events (ADE) in community dwelling older adults: a rapid realist review.HRB open research · 2022Pooled it
- Observational
- Factors associated with dying in hospital awaiting palliative care admission: a retrospective cohort study.BMC palliative care · 2026Article
- Embedding a Palliative Care Nurse Consultant Within a General Medicine Ward: A Prospective Exploratory Study.Journal of clinical nursing · 2026Article
- Hospital-to-hospice transfers in Germany: analyzing the impact of age and gender at the care transition interface.Frontiers in oncology · 2026Article
- Knowledge of CPR and Code Status Discussions in Traumatically Injured Older Adults: Does Health Literacy Matter?Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- Exploring the concept of a "friendly relationship to death" in geriatric patients.BMC geriatrics · 2025Article
- Observational
- Fulfilling end-of-life dreams: A scoping review of bucket lists in palliative and hospice care.Palliative & supportive care · 2025Article
- Factors influencing self-decision in withholding or withdrawal of life-sustaining treatments among older patients admitted to general hospital: A retrospective case-control study.Journal of Korean gerontological nursing · 2025Article
- Questions older people and caregivers ask about kidney therapies: A computer-assisted analysis.Patient education and counseling · 2025Article
- Exploring older people's end-of-life care preferences over time: A scoping review.Palliative medicine · 2025Article
- Article
- Hospital readmissions of frail older individuals: the challenge of anticipating end-of-life care.Frontiers in medicine · 2025Article
- Reconsidering dependence on life-sustaining treatment as a criterion for assisted suicide: the Italian legal unicum in comparative perspective.Frontiers in public health · 2025Article
- Integration of Geriatrics and Palliative Medicine Into a Medical Student Clinical Reasoning Curriculum.MedEdPORTAL : the journal of teaching and learning resources · 2025Article
- Personal legacy and treatment choices for serious illness: a scoping review.BMJ supportive & palliative care · 2024Article
- Technology to Support Older Adults in Home Palliative Care: A Scoping Review.The American journal of hospice & palliative care · 2024Article
- Goals of Care Among Patients With Advanced Cancer and Their Family Caregivers in the Last Years of Life.JAMA network open · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
Unpredictable disease trajectories make early clarification of end-of-life (EoL) care preferences in older patients with multimorbidity advisable. This mixed methods systematic review synthesizes studies and assesses such preferences. Two independent reviewers screened title/abstracts/full texts in seven databases, extracted data and used the Mixed Methods Appraisal Tool to assess risk of bias (RoB). We synthesized findings from 22 studies (3243 patients) narratively and, where possible, quantitatively. Nineteen studies assessed willingness to receive life-sustaining treatments (LSTs), six, the preferred place of care, and eight, preferences regarding shared decision-making processes. When unspecified, 21% of patients in four studies preferred any LST option. In three studies, fewer patients chose LST when faced with death and deteriorating health, and more when treatment promised life extension. In 13 studies, 67% and 48% of patients respectively were willing to receive cardiopulmonary resuscitation and mechanical ventilation, but willingness decreased with deteriorating health. Further, 52% of patients from three studies wished to die at home. Seven studies showed that unless incapacitated, most patients prefer to decide on their EoL care themselves. High non-response rates meant RoB was high in most studies. Knowledge of EoL care preferences of older patients with multimorbidity increases the chance such care will be provided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.