Evidence map›Paper›PMID 33383911›Full record

Observational studyGenes2020

RET Copy Number Alteration in Medullary Thyroid Cancer Is a Rare Event Correlated with RET Somatic Mutations and High Allelic Frequency.

Teresa Ramone, Chiara Mulè, Raffaele Ciampi, Valeria Bottici, Virginia Cappagli, Alessandro Prete, Antonio Matrone, Paolo Piaggi, Liborio Torregrossa, Fulvio Basolo and 2 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Genes · 2025
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Teresa RamoneEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
Chiara MulèEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
Raffaele CiampiEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
Valeria BotticiEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
Virginia CappagliEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
Alessandro PreteEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
Antonio MatroneEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
Paolo PiaggiEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.ORCID 0000-0003-2774-9161
Liborio TorregrossaDepartment of Surgical, Medical, Molecular Pathology, University of Pisa, 56124 Pisa, Italy.
Fulvio BasoloDepartment of Surgical, Medical, Molecular Pathology, University of Pisa, 56124 Pisa, Italy.ORCID 0000-0003-1657-5020
Rossella EliseiEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
Cristina RomeiEndocrine Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56124 Pisa, Italy.
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copy number variations (CNV) of the

Indexed as

Biomarkers, TumorCarcinoma, NeuroendocrineDisease-Free SurvivalDNA Copy Number VariationsDNA Mutational AnalysisFollow-Up StudiesGene FrequencyGenetic Predisposition to DiseaseGenetic TestingHumansMaleMutationNeoplasm Recurrence, LocalPolymorphism, Single NucleotidePrognosisProto-Oncogene Proteins c-retBiomarkers, TumorProto-Oncogene Proteins c-retRET protein, humancopy number variationmedullary thyroid cancerMLPARET

Identifiers

PMID33383911
PMCPMC7824333
OpenAlexW3116809163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.