Evidence map›Paper›PMID 33383887›Full record

ReviewInternational journal of molecular sciences2020

Anticancer and Immunomodulatory Benefits of Taro (

Patrícia Ribeiro Pereira, Érika Bertozzi de Aquino Mattos, Anna Carolina Nitzsche Teixeira Fernandes Corrêa, Mauricio Afonso Vericimo, Vania Margaret Flosi Paschoalin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
24.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 63 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Article
  2. Antioxidant Activity, LC-MS/MS Identification andTropical life sciences research · 2026
    Article
  3. Review
  4. Green synthesis ofFrontiers in pharmacology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Activity ofInternational journal of molecular sciences · 2023
    Article
  9. Article
  10. Review
  11. Effects of taro [Frontiers in nutrition · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Patrícia Ribeiro PereiraBiochemistry Department, Chemistry Institute, Federal University of Rio de Janeiro (UFRJ), Av. Athos da Silveira Ramos, 149, sala 545, Cidade Universitária, Rio de Janeiro (RJ) CEP 21941-909, Brazil.
Érika Bertozzi de Aquino MattosBiochemistry Department, Chemistry Institute, Federal University of Rio de Janeiro (UFRJ), Av. Athos da Silveira Ramos, 149, sala 545, Cidade Universitária, Rio de Janeiro (RJ) CEP 21941-909, Brazil.ORCID 0000-0002-4407-1068
Anna Carolina Nitzsche Teixeira Fernandes CorrêaBiochemistry Department, Chemistry Institute, Federal University of Rio de Janeiro (UFRJ), Av. Athos da Silveira Ramos, 149, sala 545, Cidade Universitária, Rio de Janeiro (RJ) CEP 21941-909, Brazil.ORCID 0000-0002-8614-8166
Mauricio Afonso VericimoBiology Institute, Fluminense Federal University (UFF), R. Alexandre Moura, No. 8, Bloco M, sala. 505, Gragoatá, Niterói CEP 24210-200, Brazil.
Vania Margaret Flosi PaschoalinBiochemistry Department, Chemistry Institute, Federal University of Rio de Janeiro (UFRJ), Av. Athos da Silveira Ramos, 149, sala 545, Cidade Universitária, Rio de Janeiro (RJ) CEP 21941-909, Brazil.ORCID 0000-0001-6093-134X
Universidade Federal do Rio de Janeiro · BRUniversidade Federal Fluminense · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 406601/2018-6Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88882.461696/2019-01Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/203.039/2015, E-26/202.815/2018, E-26/210.865/2019, E-26/202.459/2019. and E-26/200.567/2020
6 · The paper itself

Abstract

Taro corms contain valuable bioactive molecules effective against cancer and cancer-related risk factors, such as carcinogens and biological agents, several pathophysiological conditions, including oxidative stress and inflammation, while controlling metabolic dysfunctions and boosting the immunological response. Such broad effects are achieved by the taro health-influencing compounds displaying antitumoral, antimutagenic, immunomodulatory, anti-inflammatory, antioxidant, anti-hyperglycemic, and anti-hyperlipidemic activities. Taro bioactivities are attributed to the combination of tarin, taro-4-I polysaccharide, taro polysaccharides 1 and 2 (TPS-1 and TPS-2), A-1/B-2 α-amylase inhibitors, monogalactosyldiacylglycerols (MGDGs), digalactosyldiacylglycerols (DGDGs), polyphenols, and nonphenolic antioxidants. Most of these compounds have been purified and successfully challenged in vitro and in vivo, proving their involvement in the aforementioned activities. Although these health-promoting effects have been recognized since ancient times, as well as other valuable features of taro for food profit, such as hypo-allergenicity, gluten-free, and carbohydrates with medium-glycemic index, taro crop remains underexploited. The popularization of taro intake should be considered a dietary intervention strategy to be applied to improve the overall health status of the organism and as supportive therapy to manage tumorigenesis.

Indexed as

Anti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsColocasiaFeeding BehaviorHealth Impact AssessmentHumansImmunologic FactorsNutrientsPlant ExtractsPlant TubersProtective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsImmunologic FactorsNutrientsPlant ExtractsProtective AgentsCOX-2 down-regulationhealth-promoting compoundsmetabolism modulationresistant starchtaro dietary intervention

Identifiers

PMID33383887
PMCPMC7795958
OpenAlexW3113814208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.