Evidence map›Paper›PMID 33383855›Full record

ReviewInternational journal of environmental research and public health2020

Gender Differences and Quality of Life in Parkinson's Disease.

Pietro Crispino, Miriam Gino, Elena Barbagelata, Tiziana Ciarambino, Cecilia Politi, Immacolata Ambrosino, Rosalia Ragusa, Marina Marranzano, Antonio Biondi, Marco Vacante

Abstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Gender differences in non-motor symptoms in Parkinson's disease: a multicenter longitudinal study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  14. Brain sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pietro CrispinoInternal Medicine Department, Lagonegro Hospital, 85042 Lagonegro (PZ), Italy.
Miriam GinoDepartment of Internal Medicine, Rivoli Hospital, 10098 Rivoli (TO), Italy.
Elena BarbagelataDepartment of Internal Medicine, ASL 4 Chiavarese, Sestri Levante Hospital, 16039 Sestri Levante (GE), Italy.ORCID 0000-0001-7357-4388
Tiziana CiarambinoDepartment of Medical, Surgical, Neurological, Metabolic and Geriatrics Sciences, Marcianise Hospital, ASL Caserta, University of Campania "L. Vanvitelli", 81025 Naples, Italy.
Cecilia PolitiDepartment of Internal Medicine, Veneziale Hospital, 86170 Isernia, Italy.
Immacolata AmbrosinoASL Bari, DSS 13, 70023 Bari, Italy.
Rosalia RagusaHealth Technology Assessment Committee, University Hospital G. Rodolico, 95123 Catania, Italy.ORCID 0000-0002-0964-3438
Marina MarranzanoDepartment of Medical, Surgical and Advanced Sciences, University of Catania, 95123 Catania, Italy.
Antonio BiondiDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-9374-779X
Marco VacanteDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-6815-5012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease has been found to significantly affect health-related quality of life. The gender differences of the health-related quality of life of subjects with Parkinson's disease have been observed in a number of studies. These differences have been reported in terms of the age at onset, clinical manifestations, and response to therapy. In general, women with Parkinson's disease showed more positive disease outcomes with regard to emotion processing, non-motor symptoms, and cognitive functions, although women report more Parkinson's disease-related clinical manifestations. Female gender predicted poor physical functioning and socioemotional health-related quality of life, while male gender predicted the cognitive domain of health-related quality of life. Some studies reported gender differences in the association between health-related quality of life and non-motor symptoms. Depression and fatigue were the main causes of poorer health-related quality of life in women, even in the early stages of Parkinson's disease. The aim of this review was to collect the best available evidence on gender differences in the development of Parkinson's disease symptoms and health-related quality of life.

Indexed as

Parkinson DiseaseQuality of LifeSex FactorsActivities of Daily LivingDepressionFatigueFemaleHumansMaledopaminegenderlevodopaParkinson’s diseasequality of life

Identifiers

PMID33383855
PMCPMC7795924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.