Evidence map›Paper›PMID 33383783›Full record

ArticleJournal of fungi (Basel, Switzerland)2020

MixInYeast: A Multicenter Study on Mixed Yeast Infections.

Narda Medina, Juan Carlos Soto-Debrán, Danila Seidel, Isin Akyar, Hamid Badali, Aleksandra Barac, Stéphane Bretagne, Yasemin Cag, Carole Cassagne, Carmen Castro and 31 more

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Distribution ofHealthcare (Basel, Switzerland) · 2026
    Review
  3. When Fungal Prophylaxis Fails: A Rare Case ofJournal of fungi (Basel, Switzerland) · 2025
    Article
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  6. Article
  7. A clinical analysis ofFrontiers in microbiology · 2023
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  8. Liposomal amphotericin B-the future.The Journal of antimicrobial chemotherapy · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Antifungal Resistance in Clinical Isolates ofJournal of fungi (Basel, Switzerland) · 2021
    Review
  14. Pharmaceutics · 2021
    Review
  15. T2Candida for the Diagnosis and Management of InvasiveJournal of fungi (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors at 20 institutions in 14 countries.

Narda MedinaMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Juan Carlos Soto-DebránMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain.
Danila SeidelCenter for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, Germany.
Isin AkyarDepartment of Medical Microbiology, Acibadem Mehmet Ali Aydinlar University School of Medicine, 34758 Istanbul, Turkey.
Hamid BadaliInvasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari 48157-33971, Iran.ORCID 0000-0002-6010-8414
Aleksandra BaracClinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-0132-2277
Stéphane BretagneLaboratoire de Parasitologie-Mycologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), 75010 Paris, France.ORCID 0000-0001-6870-3800
Yasemin CagIstanbul Medeniyet University Goztepe Training and Research Hospital, 34722 Istanbul, Turkey.
Carole CassagneAix-Marseille University, UMR MD3 IP-TPT, 13885 Marseilles, France.
Carmen CastroMicrobiology Service, Clinical Unit of Infectious Diseases and Microbiology, Hospital Universitario Valme, 41014 Sevilla, Spain.
Arunaloke ChakrabartiDepartment of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.ORCID 0000-0003-1555-3807
Eric DannaouiUnité de Parasitologie-Mycologie, Service de Microbiologie, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris (AP-HP) Université de Paris, 75015 Paris, France.ORCID 0000-0002-2817-3830
Celia CardozoHospital Universitario Clínic, 08036 Barcelona, Spain.
Julio Garcia-RodriguezHospital Universitario La Paz, 28046 Madrid, Spain.
Juliette GuitardService de Parasitologie-Mycologie, Centre de Recherche Saint-Antoine, CRSA, AP-HP, Hôpital Saint-Antoine, Sorbonne Université, Inserm, 75012 Paris, France.ORCID 0000-0002-9782-3577
Petr HamalDepartment of Microbiology, Palacky University, Faculty of Medicine and Dentistry and University Hospital, 775 15 Olomouc, Czech Republic.ORCID 0000-0002-5361-8125
Martin HoeniglDivision of Infectious Diseases and Global Public Health, University of California San Diego, San Diego, CA 92093, USA.ORCID 0000-0002-1653-2824
Tomasz JagielskiDepartment of Medical Microbiology, Institute of Microbiology, Faculty of Biology, University of Warsaw, I. Miecznikowa 1, 02-096 Warsaw, Poland.ORCID 0000-0001-9553-5742
Sadegh KhodavaisyDivision of Molecular Biology & Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran 14167-53955, Iran.ORCID 0000-0001-8039-4991
Giuliana Lo CascioMicrobiology and Virology Unit, Department of Pathology and Diagnostic, Azienda Ospedaliera Universitaria Integrata, 30126 Verona, Italy.
María Carmen Martínez-RubioHospital Universitario de Puerto Real, 11510 Cádiz, Spain.
Joseph MeletiadisClinical Microbiology Laboratory, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Haidari, 12462 Athens, Greece.ORCID 0000-0002-8869-1509
Patricia MuñozClinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañon, 28007 Madrid, Spain.
Elżbieta OchmanDepartment of Clinical Microbiology, The Maria Skłodowska-Curie Institute of Oncology, W. K. Roentgena 5, 02-781 Warsaw, Poland.
Teresa PeláezHospital Universitario Central de Asturias (HUCA), Fundación para la Investigación Biomédica y la Innovación Biosanitaria del Principado de Asturias (FINBA), 33011 Asturias, Spain.
Ana Perez-Ayala BalzolaMicrobiology Department, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.
Juergen PrattesSection of Infectious Diseases and Tropical Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.ORCID 0000-0001-5751-9311
Emmanuel RoilidesInfectious Diseases Unit, 3rd Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Hippokration General Hospital, 54642 Thessaloniki, Greece.ORCID 0000-0002-0202-364X
Maite Ruíz-Pérez de PipaónDepartment of Infectious Diseases, Microbiology and Preventive Medicine, University Hospital Virgen del Rocío, 41013 Seville, Spain.
Raphael StaufInstitute of Clinical Hygiene, Medical Microbiology and Infectiology, Klinikum Nürnberg, Paracelsus Medical University, 90419 Nuremberg, Germany.
Jörg SteinmannInstitute of Clinical Hygiene, Medical Microbiology and Infectiology, Klinikum Nürnberg, Paracelsus Medical University, 90419 Nuremberg, Germany.
Ana Isabel Suárez-BarrenecheaInfectious disease and Clinical Microbiology Department, Virgen Macarena University Hospital, 41009 Sevilla, Spain.
Rocío TejeroUnit of Microbiology, Hospital Universitario Reina Sofía, 14004 Cordoba, Spain.
Laura TrovatoU.O.C. Laboratory Analysis Unit, A.O.U. "Policlinico-Vittorio Emanuele", 95123 Catania, Italy.
Lourdes ViñuelaServicio de Microbiología Hospital Universitario Río Hortega, 47012 Valladolid, Spain.
Thanwa WongsukDepartment of Clinical Pathology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok 10300, Thailand.
Iwona ŻakDepartment of Clinical Microbiology, Children's University Hospital of Cracow, 30-663 Kraków, Poland.
Hossein ZarrinfarAllergy Research Center, Mashhad University of Medical Sciences, Mashhad 91766-99199, Iran.ORCID 0000-0002-1449-4668
Cornelia Lass-FlörlDepartment of Hygiene und Medical Microbiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-2946-7785
Sevtap Arikan-AkdagliDepartment of Medical Microbiology, Hacettepe University Medical School, 06100 Ankara, Turkey.
Ana Alastruey-IzquierdoMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, 28220 Madrid, Spain.ORCID 0000-0001-8651-4405
Instituto de Salud Carlos III · ESNuremberg Hospital · DEUniversité Paris Cité · FRAcıbadem University · TRAix-Marseille Université · FRAzienda Ospedaliera Universitaria Integrata Verona · ITHacettepe University · TRHippocration General Hospital · GRHospital Universitario 12 De Octubre · ESHospital Universitario de Valme · ESHospital Universitario La Paz · ESHospital Universitario Puerto Real · ESHospital Universitario Reina Sofía · ESHospital Universitario Río Hortega · ESHospital Universitario Virgen del Rocío · ESHospital Universitario Virgen Macarena · ESInnsbruck Medical University · ATInserm · FRInstituto de Investigación Sanitaria del Principado de Asturias · ESIstanbul Medeniyet University · TR

Funding

Gilead Sciences research and ESCMID study group NA
6 · The paper itself

Abstract

Invasive candidiasis remains one of the most prevalent systemic mycoses, and several studies have documented the presence of mixed yeast (MY) infections. Here, we describe the epidemiology, clinical, and microbiological characteristics of MY infections causing invasive candidiasis in a multicenter prospective study. Thirty-four centers from 14 countries participated. Samples were collected in each center between April to September 2018, and they were sent to a reference center to confirm identification by sequencing methods and to perform antifungal susceptibility testing, according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST). A total of 6895 yeast cultures were identified and MY occurred in 150 cases (2.2%). Europe accounted for the highest number of centers, with an overall MY rate of 4.2% (118 out of 2840 yeast cultures). Of 122 MY cases, the most frequent combinations were

Indexed as

Candidachrome agarinvasive candidiasismix infectionspolymicrobial infectionsyeast

Identifiers

PMID33383783
PMCPMC7823447
OpenAlexW3117869657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.