ReviewAnimals : an open access journal from MDPI2020
Emerging Genetic Tools to Investigate Molecular Pathways Related to Heat Stress in Chickens: A Review.
Review in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Beyond the Chicken: Alternative Avian Models for Developmental Physiological Research.Frontiers in physiology · 2021Pooled it
- Comparative genomic and evolutionary analysis of the heat shock protein gene family in the chicken genome.Animal biotechnology · 2026Article
- Growth curve responses of two ECC-approved genotypes to locomotor, thermal, and nutritional challenges.Poultry science · 2026Article
- Transcriptome profiling analysis of heat-adapted and heat-sensitive breeder hen jejunal mucosal tissues in response to acute heat stress.BMC veterinary research · 2026Article
- Refined THI Models for Evaluating the Effects of Heat Stress on Egg Production in Thai Native and Black-Boned Chickens.Animals : an open access journal from MDPI · 2026Article
- Omics in heat stress in poultry: implications for immune responses, proteomic changes, and nutritional strategies.Veterinary research communications · 2026Review
- Multi-Omics Analysis of the Effects of Sex on Flavor Formation in Xichuan Black-Boned Chicken Meat.Animals : an open access journal from MDPI · 2026Article
- Detection of genomic regions affecting thermotolerance traits in growing pigs during acute and chronic heat stress.Genetics, selection, evolution : GSE · 2025Article
- Comparative genomics reveals common diversity and adaptation to harsh environments in the Arabian Peninsula indigenous chickens.Animal genetics · 2025Article
- Changes in Core Temperature of Cyan-Shank Partridge Chickens Exposed to Continuously Increased Ambient Temperature at Different Relative Humidity Levels.Animals : an open access journal from MDPI · 2025Article
- Comparative Transcriptome Analysis of Hens' Livers in Conventional Cage vs. Cage-Free Egg Production Systems.Veterinary medicine international · 2025Article
- Whole genome sequencing of three native chicken varieties (Common Deshi, Hilly and Naked Neck) of Bangladesh.Scientific data · 2024Article
- Genetic Analysis ofAnimals : an open access journal from MDPI · 2024Article
- Effect of genotype and nutritional and environmental challenges on growth curve dynamics of broiler chickens.Poultry science · 2024Article
- Effects of Low-Pressure Systems on Temperature, Humidity, Egg Production, and Feed Utilization Efficiency in Large-Scale Poultry Houses during Summer.Animals : an open access journal from MDPI · 2024Article
- Embryonic thermal manipulation: a potential strategy to mitigate heat stress in broiler chickens for sustainable poultry production.Journal of animal science and biotechnology · 2024Review
- Robust identification of interactions between heat-stress responsive genes in the chicken brain using Bayesian networks and augmented expression data.Scientific reports · 2024Article
- Landscape genomics reveals regions associated with adaptive phenotypic and genetic variation in Ethiopian indigenous chickens.BMC genomics · 2024Article
- Effect of heat stress on the hypothalamic expression profile of water homeostasis-associated genes in low- and high-water efficient chicken lines.Physiological reports · 2024Article
- Inflammatory response in dairy cows caused by heat stress and biological mechanisms for maintaining homeostasis.PloS one · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chicken products are the most consumed animal-sourced foods at a global level across greatly diverse cultures, traditions, and religions. The consumption of chicken meat has increased rapidly in the past few decades and chicken meat is the main animal protein source in developing countries. Heat stress is one of the environmental factors which decreases the productive performance of poultry and meat quality. Heat stress produces the over-expression of heat shock factors and heat shock proteins in chicken tissues. Heat shock proteins regulate several molecular pathways in cells in response to stress conditions, changing the homeostasis of cells and tissues. These changes can affect the physiology of the tissue and hence the production ability of chickens. Indeed, commercial chicken strains can reach a high production level, but their body metabolism, being comparatively accelerated, has poor thermoregulation. In contrast, native backyard chickens are more adapted to the environments in which they live, with a robustness that allows them to survive and reproduce constantly. In the past few years, new molecular tools have been developed, such as RNA-Seq, Single Nucleotide Polymorphisms (SNPs), and bioinformatics approaches such as Genome-Wide Association Study (GWAS). Based on these genetic tools, many studies have detected the main pathways involved in cellular response mechanisms. In this context, it is necessary to clarify all the genetic and molecular mechanisms involved in heat stress response. Hence, this paper aims to review the ability of the new generation of genetic tools to clarify the molecular pathways associated with heat stress in chickens, offering new perspectives for the use of these findings in the animal breeding field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.