Evidence map›Paper›PMID 33383654›Full record

ArticleMarine drugs2020

A Cytotoxic Porphyrin from North Pacific Brittle Star

Antonina Klimenko, Robin Huber, Laurence Marcourt, Estelle Chardonnens, Alexey Koval, Yuri S Khotimchenko, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Vladimir L Katanaev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Shallow- and Deep-WaterAntioxidants (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonina KlimenkoTranslational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.ORCID 0000-0002-8031-0425
Robin HuberSchool of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel-Servet 1, CH-1211 Geneva, Switzerland.
Laurence MarcourtSchool of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel-Servet 1, CH-1211 Geneva, Switzerland.ORCID 0000-0002-9614-1099
Estelle ChardonnensTranslational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.ORCID 0000-0002-5665-0657
Alexey KovalTranslational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.
Yuri S KhotimchenkoSchool of Biomedicine, Far Eastern Federal University, 690090 Vladivostok, Russia.
Emerson Ferreira QueirozSchool of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel-Servet 1, CH-1211 Geneva, Switzerland.ORCID 0000-0001-9567-1664
Jean-Luc WolfenderSchool of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel-Servet 1, CH-1211 Geneva, Switzerland.ORCID 0000-0002-0125-952X
Vladimir L KatanaevTranslational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.ORCID 0000-0002-7909-5617

Funding

Ministry of Science and Higher Education of Russia 13.1902.21.0012Russian Foundation for Basic Research 19-515-55013Swiss National Science Foundation 316030_164095
6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) represents the deadliest form of gynecological tumors currently lacking targeted therapies. The ethanol extract of the North Pacific brittle star

Indexed as

PhotochemotherapyAntineoplastic AgentsAquatic OrganismsCell ProliferationFemaleHumansMCF-7 CellsMolecular StructurePhotosensitizing AgentsPorphyrinsStructure-Activity RelationshipTriple Negative Breast NeoplasmsAntineoplastic AgentsPhotosensitizing AgentsPorphyrinsbreast cancercytotoxicityOphiura sarsiiphotodynamic therapyporphyrintargeted therapy

Identifiers

PMID33383654
PMCPMC7824513

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.