Evidence map›Paper›PMID 33383464›Full record

ArticleClinical neurology and neurosurgery2021

Monocular visual loss as the presenting symptom of COVID-19 infection.

Ann P Murchison, Ahmad Sweid, Robin Dharia, Thana N Theofanis, Stavropoula I Tjoumakaris, Pascal M Jabbour, Jurij R Bilyk

Open access · greenAbstract readCase Reports
In one paragraph

Article in Clinical neurology and neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. The spectrum of COVID-19-associated chorioretinal vasculopathy.American journal of ophthalmology case reports · 2023
    Article
  6. Retinal vascular occlusions in COVID-19 infection and vaccination: a literature review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Comments on coronavirus positive patients presenting with stroke-like symptoms.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021
    Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ann P MurchisonEye Emergency Room, Wills Eye Hospital & Associate Professor, Department of Emergency Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, United States; Oculoplastic and Orbital Surgery Service, Wills Eye Hospital, Philadelphia, PA, United States. Electronic address: amurchison@willseye.org.
Ahmad SweidDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, United States. Electronic address: ahmad.sweid@jefferson.edu.
Robin DhariaDepartment of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA, United States. Electronic address: robin.dharia@jefferson.edu.
Thana N TheofanisDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, United States. Electronic address: thana.theofanis@jefferson.edu.
Stavropoula I TjoumakarisDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, United States. Electronic address: stavropoula.tjoumakaris@jefferson.edu.
Pascal M JabbourDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, United States. Electronic address: pascal.jabbour@jefferson.edu.
Jurij R BilykOculoplastic and Orbital Surgery Service, Wills Eye Hospital, Philadelphia, PA, United States. Electronic address: jrbilyk@aol.com.
Thomas Jefferson University Hospital · USWills Eye Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and importanceAdditional time is needed to determine the exact impact of COVID-19 on acute cerebrovascular disease incidence, but recently published data has correlated COVID-19 to large vessel occlusion strokes. CLINICAL PRESENTATION: We report the first case of central retinal artery occlusion (CRAO) as the initial manifestation of COVID-19 infection. Subsequent neuroimaging revealed a large thrombus extending into the internal carotid artery.

conclusionThis case illustrates the need to suspect COVID-19 infection in patients presenting with retinal arterial occlusion, including individuals who are asymptomatic or minimally symptomatic for COVID-19 infection.

Indexed as

COVID-19Diagnosis, DifferentialHumansMaleMiddle AgedRetinal Artery OcclusionVision DisordersVision, MonocularCentral nervous systemCentral retinal artery occlusionCerebrovascular diseaseCOVID-19SARS-CoV-2

Identifiers

PMID33383464
PMCPMC7831816
OpenAlexW3112006015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.