Observational studyClinical neurology and neurosurgery2021
Decline in mild stroke presentations and intravenous thrombolysis during the COVID-19 pandemic: The Society of Vascular and Interventional Neurology Multicenter Collaboration.
Observational study in Clinical neurology and neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04934020 (Global Impact of the COVID 19 Pandemic on Stroke Care), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Global Impact of the COVID 19 Pandemic on Stroke Care: 1-year Follow-up Study
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of the COVID-19 pandemic on stroke admissions and treatment globally: a systematic review.BMJ open · 2023Pooled it
- The stroke meta-metric, Defect-Free Care, was maintained year-over-year within the Florida stroke registry during the COVID-19 pandemic.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2025Article
- Direct and indirect impact of SARS-CoV-2 on the brain.Human genetics · 2023Review
- Cerebrovascular Disease in COVID-19.Viruses · 2023Review
- Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.Neurology · 2023Observational
- Characteristic of Acute Ischemic Stroke Patients Based on TOAST Classification During COVID-19 Pandemic Era: A Single Centre Study.International journal of general medicine · 2023Article
- Short-Term Outcomes of Acute Stroke During COVID-19 by Race and Ethnicity in the United States: The Society of Vascular and Interventional Neurology Multicenter Collaboration.Stroke (Hoboken, N.J.) · 2022Article
- Impact of COVID-19 on the Volume of Acute Stroke Admissions: A Nationwide Survey in Japan.Neurologia medico-chirurgica · 2022Observational
- Interaction of Ethnicity and Arrival Method on Thrombectomy Delay: The Society of Vascular and Interventional Neurology Collaboration.Stroke (Hoboken, N.J.) · 2022Article
- Therapeutic Trends of Cerebrovascular Disease during the COVID-19 Pandemic and Future Perspectives.Journal of stroke · 2022Review
- Social Distancing, Stroke Admissions and Stroke Mortality During the COVID-19 Pandemic: A Multicenter, Longitudinal Study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022Article
- Impact of COVID-19 on the Incidence and Severity of Obstetric and Gynecologic Emergency Department Visits in an Integrated Health Care System.The Permanente journal · 2022Article
- Changes in ischemic stroke presentations, management and outcomes during the first year of the COVID-19 pandemic in Alberta: a population study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Article
- Stroke admissions and revascularization treatments in Denmark during COVID-19.Acta neurologica Scandinavica · 2022Article
- The Impact of COVID-19 Pandemic on Ischemic Stroke Patients in a Comprehensive Hospital.Risk management and healthcare policy · 2022Article
- Trends in Stroke Presentations before and during the COVID-19 Pandemic: A Meta-Analysis.Journal of stroke · 2022Article
- The impact of COVID-19 pandemic on treatment delay and short-term neurological functional prognosis for acute ischemic stroke during the lockdown period.Frontiers in neurology · 2022Article
- The overall impact of COVID-19 on healthcare during the pandemic: A multidisciplinary point of view.Health science reports · 2021Review
- Effect of COVID-19 on Acute Ischemic Stroke Hospitalizations and Treatments: Population-Level Experience.Stroke (Hoboken, N.J.) · 2021Article
- Impact of COVID-19 Pandemic on Stroke Severity and Mortality in the South-East of Santiago, Chile.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate overall ischemic stroke volumes and rates, specific subtypes, and clinical presentation during the COVID-19 pandemic in a multicenter observational study from eight states across US.
methodsWe compared all ischemic strokes admitted between January 2019 and May 2020, grouped as; March-May 2020 (COVID-19 period) and March-May 2019 (seasonal pre-COVID-19 period). Primary outcome was stroke severity at admission measured by NIHSS stratified as mild (0-7), moderate [8-14], and severe (>14). Secondary outcomes were volume of large vessel occlusions (LVOs), stroke etiology, IV-tPA rates, and discharge disposition.
resultsOf the 7969 patients diagnosed with acute ischemic stroke during the study period, 933 (12 %) presented in the COVID-19 period while 1319 (17 %) presented in the seasonal pre-COVID-19 period. Significant decline was observed in the mean weekly volumes of newly diagnosed ischemic strokes (98 ± 3 vs 50 ± 20,p = 0.003), LVOs (16.5 ± 3.8 vs 8.3 ± 5.9,p = 0.008), and IV-tPA (10.9 ± 3.4 vs 5.3 ± 2.9,p = 0.0047), whereas the mean weekly proportion of LVOs (18 % ±5 vs 16 % ±7,p = 0.24) and IV-tPA (10.4 % ±4.5 vs. 9.9 % ±2.4,p = 0.66) remained the same, when compared to the seasonal pre-COVID-19 period. Additionally, an increased proportion of patients presented with a severe disease (NIHSS > 14) during the COVID-19 period (29.7 % vs 24.5 %,p < 0.025). The odds of being discharged to home were 26 % greater in the COVID-19 period when compared to seasonal pre-COVID-19 period (OR:1.26, 95 % CI:1.07-1.49,p = 0.016).
conclusionsDuring COVID-19 period there was a decrease in volume of newly diagnosed ischemic stroke cases and IV-tPA administration. Patients admitted to the hospital had severe neurological clinical presentation and were more likely to discharge home.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.