ArticleJournal of neurology2021
Characterization of gait variability in multiple system atrophy and Parkinson's disease.
Article in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 41 citations in OpenAlex.
- Construct validity of instrumented gait assessments in hospital and daily life mobility in patients with Parkinson's disease and atypical Parkinson's syndromes: an exploratory study.Journal of neurology · 2026Trial
- Enhanced Gait Variability Index in Neurological and Geriatric Rehabilitation: A Scoping Review.NeuroRehabilitation · 2026Article
- Selective Motor Entropy Modulation and Targeted Augmentation for the Identification of Parkinsonian Gait Patterns Using Multimodal Gait Analysis.Life (Basel, Switzerland) · 2026Article
- Moving beyond the hospital: in-depth characterization of daily-life mobility in patients with atypical Parkinsonian disorders.NPJ Parkinson's disease · 2026Article
- IMU-based gait analysis methods: a systematic review of techniques for different body locations.Frontiers in sports and active living · 2026Review
- Potential for distinguishing the parkinsonian subtype of multiple system atrophy from Parkinson's disease: a three-dimensional gait analysis study.Frontiers in aging neuroscience · 2026Article
- Parkinson's Disease and Frailty: A Two-Way Link Across Aging.Journal of clinical medicine · 2025Review
- Characterizing Stair Ambulation Kinetics and the Effects of Dual Tasking in Parkinson's Disease.Journal of clinical medicine · 2025Article
- Gait instability is a more specific predictor of corticospinal tract function than gait speed in clinically stable multiple sclerosis.Scientific reports · 2025Article
- Digital Health in Parkinson's Disease and Atypical Parkinsonism-New Frontiers in Motor Function and Physical Activity Assessment: Review.Journal of clinical medicine · 2025Review
- Motor-Cognitive Dual-Task Cost and Associated Micro Lesions of Cerebellum and Brainstem in Multiple System Atrophy (Parkinsonian Type).Cerebellum (London, England) · 2025Article
- Differences Between Patients With Multiple System Atrophy With Predominant Parkinsonism and Parkinson's Disease Based on fNIRS and Gait Analysis.CNS neuroscience & therapeutics · 2025Article
- Applying Wearable Sensors and Machine Learning to the Diagnostic Challenge of Distinguishing Parkinson's Disease from Other Forms of Parkinsonism.Biomedicines · 2025Article
- Editorial: Digital biomarkers in movement disorders.Frontiers in neurology · 2025Article
- Inter-joint coordination with and without dopaminergic medication in Parkinson's disease: a case-control study.Journal of neuroengineering and rehabilitation · 2024Article
- Effects of physiotherapy and home-based training in parkinsonian syndromes: protocol for a randomised controlled trial (MobilityAPP).BMJ open · 2024Article
- Characterization of Walking in Mild Parkinson's Disease: Reliability, Validity and Discriminant Ability of the Six-Minute Walk Test Instrumented with a Single Inertial Sensor.Sensors (Basel, Switzerland) · 2024Article
- Identifying Subtle Motor Deficits Before Parkinson's Disease is Diagnosed: What to Look for?Journal of Parkinson's disease · 2024Review
- Gait physiotherapy with motor imagery in people with Parkinson's disease: a protocol for randomized control GAITimagery trial.Frontiers in neurology · 2024Article
- Fluctuations in Upper and Lower Body Movement during Walking in Normal Pressure Hydrocephalus and Parkinson's Disease Assessed by Motion Capture with a Smartphone Application, TDPT-GT.Sensors (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
19 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundGait impairment is a pivotal feature of parkinsonian syndromes and increased gait variability is associated with postural instability and a higher risk of falls.
objectivesWe compared gait variability at different walking velocities between and within groups of patients with Parkinson-variant multiple system atrophy, idiopathic Parkinson's disease, and a control group of older adults.
methodsGait metrics were recorded in 11 multiple system atrophy, 12 Parkinson's disease patients, and 18 controls using sensor-based gait analysis. Gait variability was analyzed for stride, swing and stance time, stride length and gait velocity. Values were compared between and within the groups at self-paced comfortable, fast and slow walking speed.
resultsMultiple system atrophy patients displayed higher gait variability except for stride time at all velocities compared with controls, while Parkinson's patients did not. Compared with Parkinson's disease, multiple system atrophy patients displayed higher variability of swing time, stride length and gait velocity at comfortable speed and at slow speed for swing and stance time, stride length and gait velocity (all P < 0.05). Stride time variability was significantly higher in slow compared to comfortable walking in patients with multiple system atrophy (P = 0.014). Variability parameters significantly correlated with the postural instability/gait difficulty subscore in both disease groups. Conversely, significant correlations between variability parameters and MDS-UPDRS III score was observed only for multiple system atrophy patients.
conclusionThis analysis suggests that gait variability parameters reflect the major axial impairment and postural instability displayed by multiple system atrophy patients compared with Parkinson's disease patients and controls.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.