Evidence map›Paper›PMID 33382264›Full record

ArticleJournal of medicinal chemistry2021

Structure-Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of

Elliot D Mock, Ioli Kotsogianni, Wouter P F Driever, Carmen S Fonseca, Jelle M Vooijs, Hans den Dulk, Constant A A van Boeckel, Mario van der Stelt

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Elliot D MockDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University and Oncode Institute, 2300 RA Leiden, Netherlands.ORCID 0000-0002-1500-2856
Ioli KotsogianniDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University and Oncode Institute, 2300 RA Leiden, Netherlands.
Wouter P F DrieverDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University and Oncode Institute, 2300 RA Leiden, Netherlands.
Carmen S FonsecaDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University and Oncode Institute, 2300 RA Leiden, Netherlands.
Jelle M VooijsDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University and Oncode Institute, 2300 RA Leiden, Netherlands.
Hans den DulkDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University and Oncode Institute, 2300 RA Leiden, Netherlands.
Constant A A van BoeckelDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University and Oncode Institute, 2300 RA Leiden, Netherlands.
Mario van der SteltDepartment of Molecular Physiology, Leiden Institute of Chemistry, Leiden University and Oncode Institute, 2300 RA Leiden, Netherlands.
Leiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AmidesCarboxylic AcidsEnzyme InhibitorsPhosphatidylethanolaminesPhospholipasesPyrimidinesStructure-Activity RelationshipAmidesCarboxylic AcidsEnzyme InhibitorsN-acylphosphatidylethanolaminePhosphatidylethanolaminesPhospholipasespyrimidinePyrimidines

Identifiers

PMID33382264
PMCPMC7816197
OpenAlexW3116193932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.