Evidence map›Paper›PMID 33381882›Full record

ArticleClinical cardiology2021

Prognostic value of aerobic capacity and exercise oxygen pulse in postaortic dissection patients.

Pascal Delsart, Camille Delahaye, Patrick Devos, Olivia Domanski, Richard Azzaoui, Jonathan Sobocinski, Francis Juthier, Andre Vincentelli, Natacha Rousse, Agnes Mugnier and 12 more

Open access · goldAbstract read
In one paragraph

Article in Clinical cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 1 country.

Pascal DelsartCHU Lille, Institut Coeur-Poumon, Lille, France.ORCID https://orcid.org/0000-0003-3091-6119
Camille DelahayeCHU Lille, Institut Coeur-Poumon, Lille, France.
Patrick DevosUniversity of Lille, CHU Lille, EA 2694 - Santé publique: épidémiologie et qualité des soins, Lille, France.
Olivia DomanskiCHU Lille, Institut Coeur-Poumon, Lille, France.
Richard AzzaouiCHU Lille, Institut Coeur-Poumon, Lille, France.
Jonathan SobocinskiCHU Lille, Institut Coeur-Poumon, Lille, France.
Francis JuthierCHU Lille, Institut Coeur-Poumon, Lille, France.
Andre VincentelliCHU Lille, Institut Coeur-Poumon, Lille, France.
Natacha RousseCHU Lille, Institut Coeur-Poumon, Lille, France.
Agnes MugnierCHU Lille, Institut Coeur-Poumon, Lille, France.
Jerome SoquetCHU Lille, Institut Coeur-Poumon, Lille, France.
Valentin LoobuyckCHU Lille, Institut Coeur-Poumon, Lille, France.
Mohamed KoussaCHU Lille, Institut Coeur-Poumon, Lille, France.
Thomas ModineCHU Lille, Institut Coeur-Poumon, Lille, France.
Bruno JegouCHU Lille, Institut Coeur-Poumon, Lille, France.
Antoine BicalCHU Lille, Institut Coeur-Poumon, Lille, France.
Ilir HysiDepartment of Cardiac Surgery of Artois, Centre Hospitalier de Lens et Hôpital Privé de Bois Bernard, Ramsay Générale de Santé, Lens, France.
Olivier FabreDepartment of Cardiac Surgery of Artois, Centre Hospitalier de Lens et Hôpital Privé de Bois Bernard, Ramsay Générale de Santé, Lens, France.
François PontanaCHU Lille, Institut Coeur-Poumon, Lille, France.
Regis MatranCHU Lille, Institut Coeur-Poumon, Lille, France.
Claire Mounier-VehierCHU Lille, Institut Coeur-Poumon, Lille, France.
David MontaigneCHU Lille, Department of Clinical Physiology & echocardiography, Univ. Lille, Inserm U1011-EGID, Lille, France.
Institut Pasteur de Lille · FRInserm · FRCentre Hospitalier de Lens · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough recommendations encourage daily moderate activities in post aortic dissection, very little data exists regarding cardiopulmonary exercise testing (CPET) to personalize those patient's physical rehabilitation and assess their cardiovascular prognosis.

designWe aimed at testing the prognostic insight of CPET regarding aortic and cardiovascular events by exploring a prospective cohort of patients followed-up after acute aortic dissection.

methodsPatients referred to our department after an acute (type A or B) aortic dissection were prospectively included in a cohort between September 2012 and October 2017. CPET was performed once optimal blood pressure control was obtained. Clinical follow-up was done after CPET for new aortic event and major cardio-vascular events (MCE) not directly related to the aorta.

resultsAmong the 165 patients who underwent CPET, no adverse event was observed during exercise testing. Peak oxygen pulse was 1.46(1.22-1.84) mlO2/beat, that is, 97 (83-113) % of its predicted value, suggesting cardiac exercise limitation in a population under beta blockers (92% of the population). During a follow-up of 39(20-51) months from CPET, 42 aortic event recurrences and 22 MCE not related to aorta occurred. Low peak oxygen pulse (<85% of predicted value) was independently predictive of aortic event recurrence, while low peak oxygen uptake (<70% of predicted value) was an independent predictor of MCE occurrence.

conclusionCPET is safe in postaortic dissection patients should be used to not only to personalize exercise rehabilitation, but also to identify those patients with the highest risk for new aortic events and MCE not directly related to aorta.

Indexed as

Exercise TestExercise ToleranceDissectionHumansOxygenOxygen ConsumptionPrognosisProspective StudiesOxygenaortic dissectioncardiopulmonary exercise testingprognosis

Identifiers

PMID33381882
PMCPMC7852169
OpenAlexW3113861594

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.