ArticleAnnals of eye science2020
Advances in the Diagnosis and Management of Acute Retinal Necrosis.
Article in Annals of eye science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical Spectrum and Perspective in Bilateral Acute Retinal Necrosis: Systematic Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Acute retinal necrosis: Report 1-Epidemiology, clinical profile, and misdiagnosis from the largest Indian case series.Indian journal of ophthalmology · 2026Article
- Incidence and clinical characterization of retinal detachment in acute retinal necrosis: a global federated database analysis.Frontiers in ophthalmology · 2026Article
- Acute Retinal Necrosis versus Progressive Outer Retinal Necrosis.Current ophthalmology reports · 2026Article
- STING activates ZBP1-mediated PANoptosis to defend against HSV-1 retinal infection.Journal of neuroinflammation · 2025Article
- Clinical findings, outcomes following management and complications of acute retinal necrosis: the experience of a tertiary eye centre in Saudi Arabia.Journal of ophthalmic inflammation and infection · 2025Article
- Eye on cytomegalovirus: Unveiling the ophthalmic impact of cytomegalovirus.World journal of virology · 2025Article
- Varicella Zoster Virus-Induced Retinitis and Retinal Detachment in an Immunocompetent Patient: A Case Report.The American journal of case reports · 2025Article
- Immune responses drive chorioretinitis and retinal pathology after neonatal CMV infection.Science advances · 2024Article
- Diagnostic and therapeutic challenges in acute retinal necrosis; an update.Eye (London, England) · 2024Review
- Article
- Case Reports: Chemokine and Cytokine Profiling in Patients with Herpetic Uveitis.International medical case reports journal · 2024Article
- Atypical presentation of acute retinal necrosis mimicking Vogt-Koyanagi-Harada disease leading to misdiagnosis: a case report.Frontiers in medicine · 2024Article
- MMP-3 and TIMP-1 as prognostic biomarkers in VZV-induced retinal necrosis.Frontiers in cellular and infection microbiology · 2024Article
- Article
- Acute retinal necrosis: clinical features, management and outcomes.International ophthalmology · 2023Article
- Ophthalmic herpes zoster with severe complications in an immunocompromised patient: A case report and review of the literature.Experimental and therapeutic medicine · 2022Article
- Advances in the microbiological diagnosis of herpetic retinitis.Frontiers in ophthalmology · 2022Review
- Acute Retinal Necrosis with Choroidal Inflammation, Optic Perineuritis, and Early Retinal Detachment: A Case Report.Case reports in ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Acute retinal necrosis (ARN) is a devastating syndrome characterized by panuveitis, retinal necrosis, and a high rate of retinal detachment that may result in poor visual outcomes if not promptly diagnosed and treated. ARN is most commonly caused by viruses with the herpesvirus family. Etiologies include varicella-zoster virus, herpes simplex virus, and cytomegalovirus, and may be promptly diagnosed by polymerase chain reaction testing of aqueous or vitreous fluid. The true incidence of ARN is not known due to its rarity; as a result, clinical treatment is often guided by retrospective case series, case reports, and expert opinion. Standard of care has evolved over time but currently includes a combination of systemic and intravitreal antiviral in conjunction with topical or oral steroids and surgical therapy as needed. Combination therapy may reduce the rate of severe vision loss and increase the rate of visual acuity gain, although further studies are needed in this area. In particular for patients with mild to moderate disease, combination therapy may reduce the rate of retinal detachment. Adjunctive therapies including oral corticosteroid and prophylactic laser barricade are incompletely studied, but corticosteroid in particular, may reduce inflammation, which also is involved in the severe disease pathogenesis observed in ARN. This review discusses the advances in diagnosis and treatment of ARN, including management with combination antiviral medication and surgical interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.