Evidence map›Paper›PMID 33381513›Full record

ArticleFrontiers in medicine2020

Nuclear and Mitochondrial Circulating Cell-Free DNA Is Increased in Patients With Inflammatory Bowel Disease in Clinical Remission.

Zuzana Vrablicova, Kristina Tomova, Lubomira Tothova, Janka Babickova, Barbora Gromova, Barbora Konecna, Robert Liptak, Tibor Hlavaty, Roman Gardlik

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05916274 (Pro-inflammatory Role of Extracellular DNA in Inflammatory Bowel Disease in Children), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05916274 nacompletednot on this mapstarted 2023, after this paper: background citation

Pro-inflammatory Role of Extracellular DNA in Inflammatory Bowel Disease in Children: Study of the cGAS-STING Pathway

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2023 to 2024Enrolled40ConditionsInflammatory Bowel Diseases, Crohn Disease, Ulcerative ColitisArmsBlood and fecal samples, Coolonic biopsies
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
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  5. Cell-Free DNA-Based Theranostics for Inflammatory Disorders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Mitochondrial function and gastrointestinal diseases.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Zuzana Vrablicova5th Department of Internal Medicine, Sub-department of Gastroenterology and Hepatology, Faculty of Medicine, Comenius University, University Hospital Bratislava, Bratislava, Slovakia.
Kristina Tomova2nd Department of Gynecology and Obstetrics, Hospital of F. D. Roosevelt, Slovak Medical University, Banska Bystrica, Slovakia.
Lubomira TothovaFaculty of Medicine, Institute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia.
Janka BabickovaFaculty of Medicine, Institute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia.
Barbora GromovaFaculty of Medicine, Institute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia.
Barbora KonecnaFaculty of Medicine, Institute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia.
Robert LiptakFaculty of Medicine, Institute of Physiology, Comenius University, Bratislava, Slovakia.
Tibor Hlavaty5th Department of Internal Medicine, Sub-department of Gastroenterology and Hepatology, Faculty of Medicine, Comenius University, University Hospital Bratislava, Bratislava, Slovakia.
Roman GardlikFaculty of Medicine, Institute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia.
Comenius University Bratislava · SKSlovak Medical University · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Crohn's diseasedeoxyribonuclease (DNase)extracellular DNAremissionulcerative colitis

Identifiers

PMID33381513
PMCPMC7768081
OpenAlexW3111143624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.