Evidence map›Paper›PMID 33381490›Full record

ArticleFrontiers in chemistry2020

Effects of the Molecular Weight of Hyaluronic Acid in a Carbon Nanotube Drug Delivery Conjugate.

Silvia Arpicco, Michał Bartkowski, Alessandro Barge, Daniele Zonari, Loredana Serpe, Paola Milla, Franco Dosio, Barbara Stella, Silvia Giordani

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Silvia ArpiccoDepartment of Drug Science and Technology, University of Torino, Turin, Italy.
Michał BartkowskiSchool of Chemical Sciences, Dublin City University (DCU), Dublin, Ireland.
Alessandro BargeDepartment of Drug Science and Technology, University of Torino, Turin, Italy.
Daniele ZonariDepartment of Drug Science and Technology, University of Torino, Turin, Italy.
Loredana SerpeDepartment of Drug Science and Technology, University of Torino, Turin, Italy.
Paola MillaDepartment of Drug Science and Technology, University of Torino, Turin, Italy.
Franco DosioDepartment of Drug Science and Technology, University of Torino, Turin, Italy.
Barbara StellaDepartment of Drug Science and Technology, University of Torino, Turin, Italy.
Silvia GiordaniSchool of Chemical Sciences, Dublin City University (DCU), Dublin, Ireland.
University of Turin · ITDublin City University · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyaluronic acid (HA) is a ubiquitous biopolymer involved in many pathophysiological roles. One HA receptor, the cluster of differentiation CD44 protein, is often overexpressed in tumor cells. As such, HA has attracted considerable interest in the development of drug delivery formulations, given its intrinsic targetability toward CD44 overexpressing cells. The present study is focused on examining the correlation of HA molecular weight with its targetability properties. A library of conjugates obtained by linking the amino group of the phospholipid 1,2-dimyristoyl-

Indexed as

cancercarbon nanotubesCD44 receptorhyaluronic acidnanocarrierphospholipidstargeted drug delivery

Identifiers

PMID33381490
PMCPMC7767879
OpenAlexW3110991216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.