Evidence map›Paper›PMID 33381457›Full record

ArticleFrontiers in oncology2020

Copy Number Analysis Reveal Genetic Risks of Penile Cancer.

Yongbo Yu, Chengwen Gao, Yuanbin Chen, Meilan Wang, Jianfeng Zhang, Xiaocheng Ma, Shuaihong Liu, Hang Yuan, Zhiqiang Li, Haitao Niu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yongbo YuUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Chengwen GaoUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yuanbin ChenUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Meilan WangNursing Department, The Shengli College, China University of Petroleum, Dongying, China.
Jianfeng ZhangUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaocheng MaUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Shuaihong LiuUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hang YuanUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhiqiang LiUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Haitao NiuUrology Department, The Affiliated Hospital of Qingdao University, Qingdao, China.
Affiliated Hospital of Qingdao University · CNQingdao University · CNChina University of Petroleum, Beijing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate copy number alterations (CNAs) in genes associated with penile cancer (PeC) and determine their correlation and prognostic ability with PeC.

methodsWhole-exome sequencing was performed for tumor tissue and matched normal DNA of 35 patients diagnosed with penile squamous cell carcinoma from 2011 to 2016. Somatic CNAs were detected using the Genome Analysis Toolkit (GATK). Retrospective clinical data were collected and analyzed. All the data were statistically analyzed using SPSS 16.0 software. The cancer-specific survival rates were estimated by Kaplan-Meier curves and compared with the log-rank test.

resultsCNAs in the

conclusion

Indexed as

copy number alterationsFAKMYCNpenile cancerTP53

Identifiers

PMID33381457
PMCPMC7768990
OpenAlexW3112846644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.