ArticleEvidence-based complementary and alternative medicine : eCAM2020
GC-MS Evaluation, Antioxidant Content, and Cytotoxic Activity of Propolis Extract from Peninsular Malaysian Stingless Bees,
Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 42 citations in OpenAlex.
- Antioxidant, Anti-Inflammatory, and Chemical Composition Analysis of In VitroMolecules (Basel, Switzerland) · 2026Article
- Identification of Bioactive Compounds and Heavy Metal Concentrations in Propolis Ethanolic Extract Produced by Malaysian Stingless Bee.Biological trace element research · 2025Article
- Quality assessment and chemical diversity of Australian propolis from Tetragonula carbonaria and Tetragonula hockingsi stingless bees.Scientific reports · 2025Article
- Phenolic Content, Antioxidant Activity and In Vitro Anti-Inflammatory and Antitumor Potential of Selected Bulgarian Propolis Samples.Biomedicines · 2025Article
- Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review.Biomedical reports · 2025Article
- Metabolic profiling, antimicrobial, anticancer, and in vitro and in silico immunomodulatory investigation of Aspergillus niger OR730979 isolated from the Western Desert, Egypt.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Evaluation of the antinociceptive activities of natural propolis extract derived from stingless beeThe Korean journal of pain · 2024Article
- Combined transcriptome and widely targeted metabolome analysis reveals the potential mechanism of HupA biosynthesis and antioxidant activity inFrontiers in plant science · 2024Article
- Differences in the biochemical content and radical scavenging activity of propolis from different parts of aRoyal Society open science · 2023Article
- Antimicrobial, Cytotoxic, andLife (Basel, Switzerland) · 2023Article
- Chemical Profile and Antioxidant Capacity of Propolis fromMolecules (Basel, Switzerland) · 2022Article
- Q-TOF LC-MS compounds evaluation of propolis extract derived from Malaysian stingless bees,Saudi journal of biological sciences · 2022Article
- Propolis: An update on its chemistry and pharmacological applications.Chinese medicine · 2022Review
- High Throughput Screening for Bioactive Components ofBioMed research international · 2022Article
- The Oral Wound Healing Potential of Thai Propolis Based on Its Antioxidant Activity and Stimulation of Oral Fibroblast Migration and Proliferation.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Chemical Characterization and Cytotoxic/Antibacterial Effects of Nine Iranian Propolis Extracts on Human Fibroblast Cells and Oral Bacteria.BioMed research international · 2022Article
- Analysis of bioactive compounds and chemical composition of Malaysian stingless bee propolis water extracts.Saudi journal of biological sciences · 2021Article
- Use of Stingless Bee Propolis and Geopropolis against Cancer-A Literature Review of Preclinical Studies.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Christia vespertilionis extract induced antiproliferation and apoptosis in breast cancer (MCF7) cells.Molecular biology reports · 2021Article
- Antiviral, Antibacterial, Antifungal, and Antiparasitic Properties of Propolis: A Review.Foods (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPropolis has been used traditionally in several countries for treating various diseases as it possessed healing properties including antioxidant and anticancer qualities. In Peninsular Malaysia,
methodThe ethanolic extract of propolis (EEP) was extracted using 80% ethanol. Identification of phytochemical contents and antioxidant properties of EEP was analysed by gas chromatography-mass spectrometry (GC-MS) and using 2, 2'-azinobis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) method, respectively. The EEP cytotoxic activity was evaluated on MCF7 and MCF 10A using 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay.
resultsPhytochemical contents of EEP demonstrated 28 compounds in which caryophyllene (99%),
conclusionThe EEP has been shown to have antioxidants and potential bioactive compounds and inhibited proliferation of the MCF7 cells. Further studies on the EEP role in the apoptosis pathway and its screening towards other cell lines will be evaluated.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.