Evidence map›Paper›PMID 33381177›Full record

ArticleJournal of oncology2020

The Influence of Systemic Inflammation Response Index on Survival Outcomes of Limited-Stage Small-Cell Lung Cancer Patients Treated with Concurrent Chemoradiotherapy.

Ahmet Kucuk, Emine Elif Ozkan, Sukran Eskici Oztep, Huseyin Mertsoylu, Berrin Pehlivan, Ugur Selek, Erkan Topkan

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  4. Nomogram for predicting overall survival after curative gastrectomy using inflammatory, nutritional and pathological factors.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Ahmet KucukMersin City Education and Research Hospital, Clinic of Radiation Oncology, Mersin, Turkey.ORCID https://orcid.org/0000-0002-5361-364X
Emine Elif OzkanSuleyman Demirel University Medical Faculty, Department of Radiation Oncology, Isparta, Turkey.
Sukran Eskici OztepMersin City Education and Research Hospital, Clinic of Radiation Oncology, Mersin, Turkey.
Huseyin MertsoyluBaskent University Medical Faculty, Department of Medical Oncology, Adana, Turkey.
Berrin PehlivanBahcesehir University, Department of Radiation Oncology, Istanbul, Turkey.
Ugur SelekKoc University, School of Medicine, Department of Radiation Oncology, Istanbul, Turkey.ORCID https://orcid.org/0000-0001-8087-3140
Erkan TopkanBaskent University Medical Faculty, Department of Radiation Oncology, Adana, Turkey.ORCID https://orcid.org/0000-0001-8120-7123
Başkent University · TRMersin Üniversitesi · TRBahçeşehir University · TRSüleyman Demirel University · TRThe University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have indicated that the systemic inflammation response index (SIRI) can efficiently predict survival outcomes in various tumor types. Thusly, in absence of comparable investigations in limited-stage small-cell lung cancers (LS-SCLCs), we aimed to retrospectively evaluate the prognostic utility of SIRI in LS-SCLC patients treated with concurrent chemoradiotherapy (CRT).

resultsSearch for the availability of an ideal SIRI cutoff that may stratify the entire patients' population into two particular groups with distinctive OS outcomes identified the 1.93 value (area under the curve (AUC): 72.9%; sensitivity: 74.6%; specificity: 70.1%): Group 1: SIRI <1.93 (

conclusionsThe results of this retrospective multi-institutional cohort analysis suggested that a pre-CRT SIRI was a strong and independent prognostic biomarker that reliably stratified LS-SCLC patients into two cohorts with significantly different OS outcomes.

Identifiers

PMID33381177
PMCPMC7759417
OpenAlexW3111876602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.