Evidence map›Paper›PMID 33381152›Full record

ArticleFrontiers in genetics2020

MiR-144-3p Targets FoxO1 to Reduce Its Regulation of Adiponectin and Promote Adipogenesis.

Weimin Lin, Yonghang Tang, Yuelei Zhao, Jindi Zhao, Lifan Zhang, Wei Wei, Jie Chen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Plasma microRNA Profiling in Type 2 Diabetes Mellitus: A Pilot Study.International journal of molecular sciences · 2023
    Article
  8. Molecular and Phenotypic Changes in FLExDUX4 Mice.Journal of personalized medicine · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. TNF-Oxidative medicine and cellular longevity · 2022
    Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Weimin LinCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Yonghang TangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Yuelei ZhaoCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Jindi ZhaoCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Lifan ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Wei WeiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Jie ChenCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs), as a series of important short-chain non-coding RNAs, play an important post-transcriptional role in many biological activities, including adipogenesis. miR-144 is significantly upregulated in type II diabetes (T2D), and is considered to be an important biomarker for T2D. However, although the occurrence of T2D is inextricably linked to adipogenesis, whether miR-144 directly regulates adipogenesis remains to be further explored. In this paper, we demonstrate that miR-144 has a higher expression level in a porcine high backfat group, and it has a significant positive effect on promoting the differentiation of pre-adipocytes.

Indexed as

adipogenesisadiponectinFoxO1miR-144-3pmiRNAs

Identifiers

PMID33381152
PMCPMC7767994
OpenAlexW3112467943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.