Evidence map›Paper›PMID 33381031›Full record

ArticleFrontiers in pharmacology2020

Suppression of Urokinase-Type Plasminogen Activator Receptor by Docosahexaenoic Acid Mediated by Heme Oxygenase-1 in 12-

Sen Lian, Shinan Li, Dhiraj Kumar Sah, Nam Ho Kim, Vinoth-Kumar Lakshmanan, Young Do Jung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Sen LianDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Southern Medical University, Guangdong, China.
Shinan LiResearch Institute of Medical Sciences, Chonnam National University Medical School, Gwangju, Korea.
Dhiraj Kumar SahResearch Institute of Medical Sciences, Chonnam National University Medical School, Gwangju, Korea.
Nam Ho KimResearch Institute of Medical Sciences, Chonnam National University Medical School, Gwangju, Korea.
Vinoth-Kumar LakshmananCentre for Preclinical and Translational Medical Research (CPTMR), Central Research Facility (CRF), Faculty of Clinical Research, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
Young Do JungResearch Institute of Medical Sciences, Chonnam National University Medical School, Gwangju, Korea.
Chonnam National University · KRSouthern Medical University · CNSri Ramachandra Institute of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urokinase-type plasminogen activator receptor (uPAR) plays a crucial role in inflammation and tumor metastasis. Docosahexaenoic acid (DHA), a representative omega-3 polyunsaturated fatty acid, has been shown to exhibit anti-inflammatory and anti-tumor properties. However, the mechanism by which DHA negatively regulates uPAR expression is not yet understood. The aim of this study was to investigate the effect of DHA on 12-

Indexed as

carbon monoxidecell invasiondocosahexaenoic acid (22:6ω-3)heme oxygenase-1urokinase plasminogen activator receptor

Identifiers

PMID33381031
PMCPMC7768974
OpenAlexW3109394517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.