ArticleFrontiers in neuroscience2020
The Interaction Between the Ventrolateral Preoptic Nucleus and the Tuberomammillary Nucleus in Regulating the Sleep-Wakefulness Cycle.
Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- A molecular integrator of sleep duration and interruption.bioRxiv : the preprint server for biology · 2026Article
- Insomnia: the gut microbiome connection, prospects for probiotic and postbiotic therapies, and future directions.Journal of advanced research · 2026Review
- Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- The ventrolateral preoptic nucleus: a multisystem integrator in sleep-wake regulation.Frontiers in neuroscience · 2026Review
- Multi-target regulatory mechanisms and clinical assessment of natural products for insomnia: a review.Frontiers in pharmacology · 2026Review
- A whole-brain male mouse atlas of long-range inputs to histaminergic neurons.Nature communications · 2025Article
- Noradrenergic tone is not required for neuronal activity-induced rebound sleep in zebrafish.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024Article
- The Orexin/Hypocretin System, the Peptidergic Regulator of Vigilance, Orchestrates Adaptation to Stress.Biomedicines · 2024Review
- Acupuncture in circadian rhythm sleep-wake disorders and its potential neurochemical mechanisms.Frontiers in neuroscience · 2024Review
- Clinical Spectrum and Trajectory of Innovative Therapeutic Interventions for Insomnia: A Perspective.Aging and disease · 2023Article
- Tfap2b acts in GABAergic neurons to control sleep in mice.Scientific reports · 2023Article
- Whole-brain mapping of histaminergic projections in mouse brain.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Dexmedetomidine, an alpha 2A receptor agonist, triggers seizures unilaterally in GAERS during the pre-epileptic phase: does the onset of spike-and-wave discharges occur in a focal manner?Frontiers in neurology · 2023Article
- Hypothalamic GABAergic neurocircuitry in the regulation of energy homeostasis and sleep/wake control.Medical review (2021) · 2022Review
- The melanopsin-mediated pupil response is reduced in idiopathic hypersomnia with long sleep time.Scientific reports · 2022Article
- Carbohydrate and sleep: An evaluation of putative mechanisms.Frontiers in nutrition · 2022Review
- Effect of Restricted Feeding on Metabolic Health and Sleep-Wake Rhythms in Aging Mice.Frontiers in neuroscience · 2021Article
- The αASN neuroArticle
- Histaminergic neurotransmission in aging and Alzheimer's disease: A review of therapeutic opportunities and gaps.Alzheimer's & dementia (New York, N. Y.)Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ventrolateral preoptic nucleus (VLPO) in the anterior hypothalamus and the tuberomammillary nucleus (TMN) in the posterior hypothalamus are critical regions which involve the regulation of sleep-wakefulness flip-flop in the central nervous system. Most of the VLPO neurons are sleep-promoting neurons, which co-express γ-aminobutyric acid (GABA) and galanin, while TMN neurons express histamine (HA), a key wake-promoting neurotransmitter. Previous studies have shown that the two regions are innervated between each other, but how to regulate the sleep-wake cycle are not yet clear. Here, bicuculline (Bic), a GABA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.