Evidence map›Paper›PMID 33380868›Full record

SynthesisCurrent oncology (Toronto, Ont.)2020

Comparison of transarterial bland and chemoembolization for neuroendocrine tumours: a systematic review and meta-analysis.

E Tai, S Kennedy, A Farrell, A Jaberi, J Kachura, R Beecroft

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Current oncology (Toronto, Ont.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

E TaiDivision of Interventional Radiology, Joint Department of Medical Imaging, University Health Network, Toronto, ON.
S KennedyDivision of Interventional Radiology, Joint Department of Medical Imaging, University Health Network, Toronto, ON.
A FarrellLibrary and Information Services, Toronto General Hospital, Toronto, ON.
A JaberiDivision of Interventional Radiology, Joint Department of Medical Imaging, University Health Network, Toronto, ON.
J KachuraDivision of Interventional Radiology, Joint Department of Medical Imaging, University Health Network, Toronto, ON.
R BeecroftDivision of Interventional Radiology, Joint Department of Medical Imaging, University Health Network, Toronto, ON.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Treatment of hepatic metastases from neuroendocrine tumours improves survival and symptom relief. Hepatic arterial embolotherapy techniques include transarterial chemoembolization (tace) and bland embolization (tae). The relative efficacy of the techniques is controversial. The purpose of the present study was to use a meta-analysis and systematic review to compare tace with tae in the treatment of hepatic metastases. Methods: A literature search identified studies comparing tace and tae for treatment of hepatic metastases. Outcomes of interest included overall survival (os), progression-free survival (pfs), radiographic response, complications, and symptom control. The hazard ratios (hrs) and odds ratios (ors) were estimated and pooled. Results: Eight studies and 504 patients were included. No statistically significant differences between tace and tae were observed for os at 1, 2, and 5 years or for hrs [1-year or: 0.72; 95% confidence interval (ci): 0.27 to 1.94; Conclusions: No statistically significant differences between tace and tae were observed for os and pfs.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsNeuroendocrine TumorsHumansTreatment Outcomebland embolizationchemoembolizationhepatic metastasesNeuroendocrine tumours

Identifiers

PMID33380868
PMCPMC7755439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.