ArticleThe Korean journal of pain2021
Atypical triggers in trigeminal neuralgia: the role of A-delta sensory afferents in food and weather triggers.
Article in The Korean journal of pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.
- The efficacy of acupuncture for trigeminal neuralgia: an overview of systematic reviews.Frontiers in neurology · 2024Pooled it
- Quantitative Sensory Testing Identifies Altered Thermal and Pain Processing in Trigeminal Neuralgia.European journal of neurology · 2026Article
- Impact of climatic factors on trigeminal neuralgia and facial neuropathy in primary care during a fourteen-year time-series study.Scientific reports · 2026Article
- Pathogenesis, Diagnosis, and Management of Trigeminal Neuralgia: A Narrative Review.Journal of clinical medicine · 2025Review
- E44Q mutation in NaHeliyon · 2021Article
- Role of voltage-gated sodium channels in axonal signal propagation of trigeminal ganglion neurons after infraorbital nerve entrapment.Neurobiology of pain (Cambridge, Mass.)Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrigeminal neuralgia is a debilitating craniofacial pain syndrome that is characterized by paroxysms of intense, short-lived electric shock-like pains in the trigeminal nerve distribution. Recently, the presence of triggers has become one of the key diagnostic criteria in the 3rd edition of the International Classification of Headache Disorders. Light touch is the most common trigger, however other non-mechanical triggers, such as cold weather and certain foods, have been thought to provoke trigeminal neuralgia anecdotally. We aimed to characterize the prevalence and characteristics of these atypical triggers.
methodsWe conducted a retrospective, cross-sectional study of atypical triggers in trigeminal neuralgia patients seen in a tertiary pain clinic in Singapore. Patients were recruited
resultsA total of 60 patients met the inclusion criteria. Weather triggers were observed in 12 patients (20%), of which five patients (8%) reported strong winds, 4 patients (7%) reported cold temperatures, and 3 patients (5%) reported cold winds as triggers. Fifteen patients (25%) had a specific food trigger, of which 10 patients (17%) reported hard or tough food, 5 patients (8%) reported hot/cold food, 4 patients (7%) reported spicy food, and 2 patients (3%) reported sweet food as triggers.
conclusionsAlthough trigeminal neuralgia is most commonly triggered by mechanical stimuli, atypical triggers such as cold temperatures and certain foods are seen in a significant proportion of patients. These atypical triggers may share a common pathway of sensory afferent Aδ fiber activation.
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