Pulmonary embolism in COVID-19: D-dimer threshold selection should not be based on maximising Youden's index.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Inflammatory-Thrombotic Phenotypes and Outcomes in COVID-19-Associated Pulmonary Embolism: A Single-Center Cohort Study.Biomedicines · 2025
   Article
2. Distinct age-adjusted D-dimer threshold to rule out acute pulmonary embolism in outpatients and inpatients.The clinical respiratory journal · 2024
   Article
3. Pulmonary embolism at CT pulmonary angiography in patients with COVID-19 at a tertiary care center in Nepal: a cross-sectional study.Annals of medicine and surgery (2012) · 2023
   Article
4. Predictors and outcomes of acute pulmonary embolism in COVID-19; insights from US National COVID cohort collaborative.Respiratory research · 2023
   Article
5. What level of D-dimers can safely exclude pulmonary embolism in COVID-19 patients presenting to the emergency department?European radiology · 2022
   Article
6. Clinical and operational impact of rapid point-of-care SARS-CoV-2 detection in an emergency department.The American journal of emergency medicine · 2021
   Article
7. Routine screening for pulmonary embolism in COVID-19 patients at the emergency department: impact of D-dimer testing followed by CTPA.Journal of thrombosis and thrombolysis · 2021
   Article
8. Pulmonary Embolism in COVID-19 Patients: A Retrospective Case-Control Study.Cureus · 2021
   Article
9. Pulmonary CT angiography in the first wave of the COVID-19 pandemic: Comparison between patients with and without infection and with a pre-pandemic series.Radiologia
   Article
10. Role of peak D-dimer in predicting mortality and venous thromboembolism in COVID-19 patients.Science progress
    Article

Corrections and comments

• Comment on
  Elevated D-dimers and lack of anticoagulation predict PE in severe COVID-19 patients.2020

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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