ArticleClinical journal of the American Society of Nephrology : CJASN2020
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Article in Clinical journal of the American Society of Nephrology : CJASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
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34citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Trans-ethnic genome-wide association study of blood metabolites in the Chronic Renal Insufficiency Cohort (CRIC) study.Kidney international · 2022Pooled it
- Metabolomic Signatures of Inflammation in Chronic Kidney Disease.Kidney medicine · 2026Article
- Genome-wide association studies of missing metabolite measures from two population-based studies.Genome biology · 2026Article
- Alterations of Plasma Metabolites Associated with Sickle Cell Trait.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Systematic Evaluation of Plasma and Urine Metabolites to Predict the Risk of Adverse Kidney-related Outcomes in Chronic Kidney Disease: The GCKD Study∗.Kidney medicine · 2026Article
- The Effects of Tributyrin on Immune Function, Antioxidant Capacity, and Metabolomics in Young Pigeons.Animals : an open access journal from MDPI · 2026Article
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- Plasma Metabolites Associated with CKD Stage in Autosomal Dominant Tubulointerstitial Kidney Disease.Kidney360 · 2026Article
- Integration of metabolomic and genetic data reveals novel variants underpinning the human metabolome: the Coronary Artery Risk Development in Young Adults (CARDIA) study.medRxiv : the preprint server for health sciences · 2026Article
- A plasma N-acetyl amino acid panel for type 2 diabetes discrimination built by targeted LC-MS/MS: A case-control study.Frontiers in medicine · 2026Article
- Mendelian Randomization Study on Serum Metabolites and Diabetic Nephropathy Risk: Identifying Potential Biomarkers for Early Intervention.Current pharmaceutical design · 2026Article
- Causal associations between circulating metabolites and chronic kidney disease: a Mendelian randomization study.Renal failure · 2025Article
- Urinary acetylated protein as a biomarker of lupus nephritis: a prospective cohort study.Arthritis research & therapy · 2025Article
- Comprehensive and quantitative urinary metabolomic profiling for improved characterization of diabetic nephropathy.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Plasma and Urine Metabolites Associated With Nondiabetic Chronic Kidney Disease: The HELIUS Study.Kidney medicine · 2025Article
- Multiplatform Metabolomic Profiling of the Unilateral Ureteral Obstruction Murine Model of CKD.International journal of molecular sciences · 2025Article
- Potential non-invasive biomarkers of chronic sleep disorders identified by salivary metabolomic profiling among middle-aged Japanese men.Scientific reports · 2025Article
- Identification of Six Cerebrospinal Fluid Metabolites Causally Associated with Anorexia Nervosa Risk: A Mendelian Randomization Analysis.International journal of molecular sciences · 2025Article
- Analyses of Saliva Metabolome Reveal Patterns of Metabolites That Differentiate SARS-CoV-2 Infection and COVID-19 Disease Severity.Metabolites · 2025Article
- A roadmap to precision medicine through post-genomic electronic medical records.Nature communications · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 8 institutions in 2 countries.
Shengyuan LuoDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.ORCID 0000-0002-3235-6832
Aditya SurapaneniDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Zihe ZhengDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0003-0040-4016
Eugene P RheeDivision of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Josef CoreshDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.ORCID 0000-0002-4598-0669
Adriana M HungGeriatric Research Education Clinical Center, Veteran Administration Tennessee Valley Health Care System, Nashville, Tennessee.ORCID 0000-0002-3203-1608
Girish N NadkarniThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Bing YuDepartment of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Sciences Center at Houston School of Public Health, Houston, Texas.
Eric BoerwinkleDepartment of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Sciences Center at Houston School of Public Health, Houston, Texas.
Adrienne TinDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.ORCID 0000-0002-4207-5866
Dan E ArkingMcKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Inga SteinbrennerInstitute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Pascal SchlosserInstitute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-8460-0462
Anna KöttgenDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.ORCID 0000-0002-4671-3714
Morgan E GramsDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
Johns Hopkins University · USUniversity of Freiburg · DEBaylor College of Medicine · USHarvard University · USIcahn School of Medicine at Mount Sinai · USThe University of Texas Health Science Center at Houston · USUniversity of Pennsylvania · USVA Tennessee Valley Healthcare System · US
Funding
Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8MGenome-Wide Association Analysis in Essential Hypertension (FEHGAS study)R01HL086694 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ARAVINDA CHAKRAVARTI · 2007 to 2026
$21.2MEpidemiology of Venous Thrombosis & Pulmonary EmbolismR01HL059367 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI TANG, WEIHONG · 1998 to 2024
$11.8MMulti-Omics and Chronic Kidney Disease: Correlation with HistologyR01DK108803 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Morgan Erika Grams, EUGENE P. RHEE · 2016 to 2026
$6.4MProteomic Approach to CKD Biomarker Discovery and ValidationU01DK085689 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI CORESH, JOSEF · 2009 to 2019
$5.6MGenome-Wide Association for Loci Influencing CHD and Other Heart, Lung and BloodR01HL087641 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BOERWINKLE, ERIC A. · 2006 to 2008
$3.7MIntegrative Omics, Chronic Kidney Disease, and Adverse Outcomes in Older AdultsR01DK124399 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, Morgan Erika Grams · 2020 to 2026
$3.6MMetabolic Signatures Underlying Cardiac Function for Heart Failure in Multi-Ethnic PopulationsR01HL141824 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YU, BING · 2018 to 2021
$3.1MMetabolomics of CKD and CKD ProgressionU01DK106981 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RHEE, EUGENE P. · 2015 to 2019
$2.2MGWA for Gene-Environment Interaction Effects Influencing CHDU01HG004402 · NHGRI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BOERWINKLE, ERIC A. · 2007 to 2009
$1.6MNCRR NIH HHS UL1 RR025005NHGRI NIH HHS U01 HG004402NHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INHLBI NIH HHS R01 HL059367NHLBI NIH HHS R01 HL086694NHLBI NIH HHS R01 HL087641NHLBI NIH HHS R01 HL141824NIDDK NIH HHS R01 DK108803NIDDK NIH HHS R01 DK124399NIDDK NIH HHS U01 DK085689NIDDK NIH HHS U01 DK106981
Abstract
BACKGROUND AND
objectivesGenetic variants in DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted analyses among participants with genetic and/or serum metabolomic data in the African American Study of Kidney Disease and Hypertension (AASK;
resultsOf 31 N-acetylated amino acids evaluated, the circulating and urinary levels of 14 were associated with rs13538 (
conclusionsWe demonstrate significant associations between an
Indexed as
AcetylationAcetyltransferasesAdultAgedAged, 80 and overAmino AcidsBlack or African AmericanBlack PeopleDisease ProgressionFemaleFollow-Up StudiesGlomerular Filtration RateHistidineHumansKidney Failure, ChronicMaleAcetyltransferasesAmino AcidsHistidineMethylhistidinesN-acetyl-3-methylhistidineN-acetylhistidineNAT8 protein, humanN(delta)-acetylornithineOrnithineAASK (African American Study of Kidney Disease and Hypertension)acetylationamino acidschronic kidney diseaseend-stage renal diseasehuman geneticsmetabolism
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.