Evidence map›Paper›PMID 33380402›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2020

[

Huizhi Zhu, Kun Wang, Lei Yang, Qingwen Xu, Fengchun Ren, Xiangguo Liu

Open access · greenAbstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Huizhi ZhuDepartment of Respiratory Medicine, First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui University of Chinese Medicine, Hefei 230031, China.
Kun WangGraduate School, Anhui University of Chinese Medicine, Hefei 230031, China.
Lei YangGraduate School, Anhui University of Chinese Medicine, Hefei 230031, China.
Qingwen XuGraduate School, Anhui University of Chinese Medicine, Hefei 230031, China.
Fengchun RenGraduate School, Anhui University of Chinese Medicine, Hefei 230031, China.
Xiangguo LiuCollege of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230031, China.
Anhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo observe the effect of

methodsFifty SD rats were randomized divided into normal control (NC) group, asthmatic model group, BMSCs transplantation group, BMSCs + dexamethasone (0.0625 mg/kg daily) group, and BMSCs+YHPC granule (3.5 g/kg daily) group. In all but the normal control group, asthmatic rat models were established by ovalbumin challenge, and BMSCs (1×10

resultsCompared with the normal control rats, the asthmatic rats exhibited significantly increased expressions of CXCR4, IL-4, Notch1, Jagged1, RBP-J, and Hes1 mRNA and Notch1, Jagged1, and Hes1 proteins and lowered expressions of INF-γ mRNA and miR-139-5p in the lung tissues (

conclusionsYHPC granule can enhance the inhibitory effect of BMSCs homing on Th2 inflammatory response in asthmatic rats by up-regulating miR-139-5p and down-regulating Notch1/Hes1 pathway.

Indexed as

AsthmaMesenchymal Stem CellsMicroRNAsAnimalsDrugs, Chinese HerbalRatsRats, Sprague-DawleyReceptor, Notch1Transcription Factor HES-1Drugs, Chinese HerbalHes1 protein, ratMicroRNAsMIRN139 microRNA, ratNotch1 protein, ratReceptor, Notch1Transcription Factor HES-1yangheasthmabone marrow-derived mesenchymal stem cellshomingNotch1/Hes1 signaling pathwayYanghe Pingchuan granule

Identifiers

PMID33380402
PMCPMC7835696
OpenAlexW3117530725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.