Evidence map›Paper›PMID 33380323›Full record

ArticleBMC urology2020

Cerebral oxygenation in 45-degree trendelenburg position for robot-assisted radical prostatectomy: a single-center, open, controlled pilot study.

Clemens Wiesinger, Dominik Stefan Schoeb, Mathias Stockhammer, Emir Mirtezani, Lukas Mitterschiffthaler, Helga Wagner, Johann Knotzer, Walter Pauer

Open access · goldAbstract readControlled Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Clemens WiesingerDepartment of Urology, Wels-Grieskirchen Medical-Center, Grieskirchner Straße 42, 4600, Wels, Austria.
Dominik Stefan SchoebDepartment of Urology, Faculty of Medicine, Medical Center - University of Freiburg, Hugstetterstr. 55, 79106, Freiburg, Germany. dominik.stefan.schoeb@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0001-6394-7064
Mathias StockhammerDepartment of Urology, BHB Salzburg, Kajetanerplatz 1, 5010, Salzburg, Salzburg, Austria.
Emir MirtezaniDepartment of Urology, Wels-Grieskirchen Medical-Center, Grieskirchner Straße 42, 4600, Wels, Austria.
Lukas MitterschiffthalerDepartment of Anesthesiology and Intensive Care II, Wels-Grieskirchen Medical Center, Grieskirchner Straße 42, 4600, Wels, Austria.
Helga WagnerMedical Statistics and Biometry, Institute for Applied Statistics, Johannes Kepler University Linz, Altenbergerstrasse 69, 4040, Linz, Austria.
Johann KnotzerDepartment of Anesthesiology and Intensive Care II, Wels-Grieskirchen Medical Center, Grieskirchner Straße 42, 4600, Wels, Austria.
Walter PauerDepartment of Urology, Wels-Grieskirchen Medical-Center, Grieskirchner Straße 42, 4600, Wels, Austria.
Klinikum Wels-Grieskirchen · ATJohannes Kepler University of Linz · ATUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWithin the last decade, robotically-assisted laparoscopic prostatectomy (RALP) has become the standard for treating localized prostate cancer, causing a revival of the 45° Trendelenburg position. In this pilot study we investigated effects of Trendelenburg position on hemodynamics and cerebral oxygenation in patients undergoing RALP.

methodsWe enrolled 58 patients undergoing RALP and 22 patients undergoing robot-assisted partial nephrectomy (RAPN) (control group) in our study. Demographic patient data and intraoperative parameters including cerebral oxygenation and cerebral hemodynamics were recorded for all patients. Cerebral function was also assessed pre- and postoperatively via the Mini Mental Status (MMS) exam. Changes in parameters during surgery were modelled by a mixed effects model; changes in the MMS result were evaluated using the Wilcoxon signed rank test.

resultsPreoperative assessment of patient characteristics, standard blood values and vital parameters revealed no difference between the two groups.

conclusionsApplying a 45° Trendelenburg position causes no difference in postoperative brain function, and does not alter cerebral oxygenation during a surgical procedure lasting up to 5 h. Further studies in larger patient cohorts will have to confirm these findings.

trial registrationGerman Clinical Trial Registry; DRKS00005094; Registered 12th December 2013-Retrospectively registered; https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00005094 .

Indexed as

Head-Down TiltLaparoscopyRobotic Surgical ProceduresAgedBrainHumansMaleMiddle AgedOxygenPatient PositioningPilot ProjectsProstatectomyOxygenHead-down tiltIntraoperativeLaparoscopy/adverse effectsMonitoringProstatectomy/adverse effects*Robotic surgical procedures/adverse effectsRobotic surgical procedures/methods

Identifiers

PMID33380323
PMCPMC7772899
OpenAlexW3113811672

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.