Evidence map›Paper›PMID 33380286›Full record

ArticleVirulence2021

Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells.

Erpeng Zhu, Huawei Wu, Wenxian Chen, Yuwei Qin, Jiameng Liu, Shuangqi Fan, Shengming Ma, Keke Wu, Qian Mao, Chaowei Luo and 5 more

Open access · goldAbstract read
In one paragraph

Article in Virulence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Strategies of Classical Swine Fever Immune Evasion.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. The Multi-Faceted Role of Autophagy During Animal Virus Infection.Frontiers in cellular and infection microbiology · 2022
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Erpeng ZhuDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Huawei WuDepartment of Viral Biologics, China Institute of Veterinary Drug Control , Beijing, China.
Wenxian ChenDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Yuwei QinDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Jiameng LiuDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Shuangqi FanDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Shengming MaDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Keke WuDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Qian MaoDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Chaowei LuoDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Yixian QinDepartment of Viral Biologics, China Institute of Veterinary Drug Control , Beijing, China.
Lin YiDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Hongxing DingDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Mingqiu ZhaoDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
Jinding ChenDepartment of Microbiology and Immunology, College of Veterinary Medicine, South China Agricultural University , Guangzhou, China.
South China Agricultural University · CNKey Laboratory of Guangdong Province · CNChina Institute of Veterinary Drug Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoplasmic reticulum stress (ERS)-mediated autophagy is indispensable for modulation of replication and pathogenesis of numerous mammalian viruses. We have previously shown that classical swine fever virus (CSFV) infection induces ERS-mediated autophagy for maintaining viral replication both

Indexed as

AutophagyCell SurvivalVirus ReplicationAnimalsCell LineClassical Swine Fever VirusCytokineseIF-2 KinaseEndoplasmic Reticulum StressEndoribonucleasesRNA, Small InterferingSignal TransductionSwineCytokineseIF-2 KinaseEndoribonucleasesRNA, Small InterferingAutophagyclassical swine fever virusendoplasmic reticulum stressIRE1PERKproinflammatory cytokinesvirus replication

Identifiers

PMID33380286
PMCPMC7781608
OpenAlexW3118229450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.