Evidence map›Paper›PMID 33379392›Full record

ReviewInternational journal of molecular sciences2020

An Insight into the Role of Non-Porphyrinoid Photosensitizers for Skin Wound Healing.

Mariana C S Vallejo, Nuno M M Moura, Maria Amparo Ferreira Faustino, Adelaide Almeida, Idalina Gonçalves, Vanda V Serra, Maria Graça P M S Neves

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Wound healing and photodynamic potential ofFrontiers in pharmacology · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Porphyrin Photosensitizers Grafted in Cellulose Supports: A Review.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. The Role of Porphyrinoid Photosensitizers for Skin Wound Healing.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mariana C S VallejoLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-7310-9766
Nuno M M MouraLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-9373-7006
Maria Amparo Ferreira FaustinoLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-4423-3802
Adelaide AlmeidaCESAM, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-8422-8664
Idalina GonçalvesCICECO, Department of Materials and Ceramic Engineering, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-2098-2112
Vanda V SerraCentro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal.
Maria Graça P M S NevesLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-7953-8166
Rede de Química e Tecnologia · PTUniversity of Aveiro · PTUniversity of Lisbon · PT

Funding

Fundação para a Ciência e a Tecnologia CEECIND/00430/2017Fundação para a Ciência e a Tecnologia REF. 048-88-ARH/2018
6 · The paper itself

Abstract

The concept behind photodynamic therapy (PDT) is being successfully applied in different biomedical contexts such as cancer diseases, inactivation of microorganisms and, more recently, to improve wound healing and tissue regeneration. The effectiveness of PDT in skin treatments is associated with the role of reactive oxygen species (ROS) produced by a photosensitizer (PS), which acts as a "double agent". The release of ROS must be high enough to prevent microbial growth and, simultaneously, to accelerate the immune system response by recruiting important regenerative agents to the wound site. The growing interest in this subject is reflected by the increasing number of studies concerning the optimization of relevant experimental parameters for wound healing via PDT, namely, light features, the structure and concentration of the PS, and the wound type and location. Considering the importance of developing PSs with suitable features for this emergent topic concerning skin wound healing, in this review, a special focus on the achievements attained for each PS class, namely, of the non-porphyrinoid type, is given.

Indexed as

AnimalsHumansPhotochemotherapyPhotosensitizing AgentsPorphyrinsReactive Oxygen SpeciesSkinWound HealingPhotosensitizing AgentsPorphyrinsReactive Oxygen Speciesphotobondingphotodynamic processphotosensitizerreactive oxygen speciesskinwound healing

Identifiers

PMID33379392
PMCPMC7795024
OpenAlexW3115987866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.