Evidence map›Paper›PMID 33379374›Full record

ArticleMolecules (Basel, Switzerland)2020

A Novel Resorbable Composite Material Containing Poly(ester-co-urethane) and Precipitated Calcium Carbonate Spherulites for Bone Augmentation-Development and Preclinical Pilot Trials.

Claudia Rode, Ralf Wyrwa, Juergen Weisser, Matthias Schnabelrauch, Marijan Vučak, Stefanie Grom, Frank Reinauer, Adrian Stetter, Karl Andreas Schlegel, Rainer Lutz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Claudia RodeBiomaterials Department, INNOVENT e. V., Prüssingstrasse 27B, 07745 Jena, Germany.
Ralf WyrwaBiomaterials Department, INNOVENT e. V., Prüssingstrasse 27B, 07745 Jena, Germany.ORCID 0000-0003-4556-6510
Juergen WeisserBiomaterials Department, INNOVENT e. V., Prüssingstrasse 27B, 07745 Jena, Germany.
Matthias SchnabelrauchBiomaterials Department, INNOVENT e. V., Prüssingstrasse 27B, 07745 Jena, Germany.ORCID 0000-0002-1968-8058
Marijan VučakSchaefer Kalk GmbH & Co. KG, Louise-Seher-Straße 6, 65582 Diez, Germany.
Stefanie GromKarl Leibinger Medizintechnik GmbH & Co. KG, a Company of the KLS Martin Group, Kolbinger Straße 10, 78570 Mühlheim an der Donau, Germany.
Frank ReinauerKarl Leibinger Medizintechnik GmbH & Co. KG, a Company of the KLS Martin Group, Kolbinger Straße 10, 78570 Mühlheim an der Donau, Germany.
Adrian StetterClinic for Oral and Maxillofacial Surgery, Universitätsklinikum Erlangen, Glückstrasse 11, 91054 Erlangen, Germany.
Karl Andreas SchlegelClinic for Oral and Maxillofacial Surgery, Universitätsklinikum Erlangen, Glückstrasse 11, 91054 Erlangen, Germany.
Rainer LutzClinic for Oral and Maxillofacial Surgery, Universitätsklinikum Erlangen, Glückstrasse 11, 91054 Erlangen, Germany.
Innovent · DEUniversitätsklinikum Erlangen · DEKLS Martin (Germany) · DE

Funding

German Federal Ministry of Economic Affairs and Energy INNO-KOM, MF130161
6 · The paper itself

Abstract

Polyurethanes have the potential to impart cell-relevant properties like excellent biocompatibility, high and interconnecting porosity and controlled degradability into biomaterials in a relatively simple way. In this context, a biodegradable composite material made of an isocyanate-terminated co-oligoester prepolymer and precipitated calcium carbonated spherulites (up to 60%

Indexed as

3T3 CellsAnimalsBiocompatible MaterialsBone DevelopmentBone RegenerationBone SubstitutesCalcium CarbonateCell LineCompressive StrengthFemaleMiceOsteoblastsOsteogenesisPilot ProjectsPolyestersPolyurethanesBiocompatible MaterialsBone SubstitutesCalcium CarbonatePolyestersPolyurethanesbioresorbable compositebone regenerationcalcium carbonatedegradable polyurethanefoam

Identifiers

PMID33379374
PMCPMC7795954
OpenAlexW3115205659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.