Evidence map›Paper›PMID 33379360›Full record

ArticleInternational journal of molecular sciences2020

Characterization of New Proteomic Biomarker Candidates in Mucopolysaccharidosis Type IVA.

Víctor J Álvarez, Susana B Bravo, Maria Pilar Chantada-Vazquez, Cristóbal Colón, María J De Castro, Montserrat Morales, Isidro Vitoria, Shunji Tomatsu, Francisco J Otero-Espinar, María L Couce

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Novel Phenotypical and Biochemical Findings in Mucolipidosis Type II.International journal of molecular sciences · 2025
    Article
  8. Article
  9. Article
  10. Mucopolysaccharidosis IVA: Current Disease Models and Drawbacks.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Proteomics in Inherited Metabolic Disorders.International journal of molecular sciences · 2022
    Review
  15. Review
  16. Article
  17. Plasma Proteomic Analysis in Morquio A Disease.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Víctor J ÁlvarezDepartment of Forensic Sciences, Pathology, Gynecology and Obstetrics, Pediatrics, Neonatology Service, Department of Paediatrics, Hospital Clínico Universitario de Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), CIBERER, MetabERN, 15706 Santiago de Compostela, Spain.
Susana B BravoProteomic Platform, Health Research Institute of Santiago de Compostela (IDIS), Hospital Clínico Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0001-7615-3079
Maria Pilar Chantada-VazquezProteomic Platform, Health Research Institute of Santiago de Compostela (IDIS), Hospital Clínico Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.
Cristóbal ColónDepartment of Forensic Sciences, Pathology, Gynecology and Obstetrics, Pediatrics, Neonatology Service, Department of Paediatrics, Hospital Clínico Universitario de Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), CIBERER, MetabERN, 15706 Santiago de Compostela, Spain.ORCID 0000-0002-9711-2812
María J De CastroDepartment of Forensic Sciences, Pathology, Gynecology and Obstetrics, Pediatrics, Neonatology Service, Department of Paediatrics, Hospital Clínico Universitario de Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), CIBERER, MetabERN, 15706 Santiago de Compostela, Spain.
Montserrat MoralesMinority Diseases Unit Hospital Universitario12 de Octubre, 28041 Madrid, Spain.
Isidro VitoriaNutrition and Metabolophaties Unit, Hospital Universitario La Fe, 46026 Valencia, Spain.ORCID 0000-0003-4450-1213
Shunji TomatsuSkeletal Dysplasia Lab Nemours Biomedical Research Nemours/Alfred I. du Pont Hospital for Children, 1600 Rockland Road., Wilmington, DE 19803, USA.ORCID 0000-0002-0673-2160
Francisco J Otero-EspinarParaquasil Platform, Health Research Institute of Santiago de Compostela (IDIS), Hospital Clínico Universitario de Santiago de Compostela, 15706 Santiago de Compostela, Spain.ORCID 0000-0001-9030-2253
María L CouceDepartment of Forensic Sciences, Pathology, Gynecology and Obstetrics, Pediatrics, Neonatology Service, Department of Paediatrics, Hospital Clínico Universitario de Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), CIBERER, MetabERN, 15706 Santiago de Compostela, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucopolysaccharidosis type IVA (MPS IVA) is a lysosomal storage disease caused by mutations in the

Indexed as

ProteomicsAdolescentAdultBiomarkersCase-Control StudiesChildChild, PreschoolDown-RegulationEnzyme Replacement TherapyFemaleHumansInfantLeukocytesMaleMucopolysaccharidosis IVProtein Interaction MapsBiomarkersbiomarkersenzyme replacement therapylysosomal disordersproteomics

Identifiers

PMID33379360
PMCPMC7795692

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.