Evidence map›Paper›PMID 33379243›Full record

ArticleMolecules (Basel, Switzerland)2020

Protective Effect of Ferulic Acid against Hydrogen Peroxide Induced Apoptosis in PC12 Cells.

Hironao Nakayama, Masako Nakahara, Erina Matsugi, Midori Soda, Tomoka Hattori, Koki Hara, Ayuki Usami, Chiaki Kusumoto, Shigeki Higashiyama, Kiyoyuki Kitaichi

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. How gallic acid regulates molecular signaling: role in cancer drug resistance.Medical oncology (Northwood, London, England) · 2023
    Review
  10. ACS omega · 2023
    Article
  11. Article
  12. Pharmacological and Chemical Potential ofPlants (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hironao NakayamaDepartment of Medical Science and Technology, Hiroshima International University, Higashi-hiroshima, Hiroshima 739-2695, Japan.ORCID 0000-0002-9371-2650
Masako NakaharaDepartment of Medical Science and Technology, Hiroshima International University, Higashi-hiroshima, Hiroshima 739-2695, Japan.
Erina MatsugiDepartment of Medical Science and Technology, Hiroshima International University, Higashi-hiroshima, Hiroshima 739-2695, Japan.
Midori SodaLaboratory of Pharmaceutics, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
Tomoka HattoriLaboratory of Pharmaceutics, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
Koki HaraLaboratory of Pharmaceutics, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
Ayuki UsamiLaboratory of Pharmaceutics, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
Chiaki KusumotoDepartment of Medical Science and Technology, Hiroshima International University, Higashi-hiroshima, Hiroshima 739-2695, Japan.
Shigeki HigashiyamaDivision of Cell Growth and Tumor Regulation, Proteo-Science Center, Ehime University, Toon, Shitsukawa, Ehime 791-0295, Japan.
Kiyoyuki KitaichiLaboratory of Pharmaceutics, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
Gifu Pharmaceutical University · JPHiroshima International University · JPEhime University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferulic Acid (FA) is a highly abundant phenolic phytochemical which is present in plant tissues. FA has biological effects on physiological and pathological processes due to its anti-apoptotic and anti-oxidative properties, however, the detailed mechanism(s) of function is poorly understood. We have identified FA as a molecule that inhibits apoptosis induced by hydrogen peroxide (H

Indexed as

Adrenal Gland NeoplasmsAnimalsAntioxidantsApoptosisBrain-Derived Neurotrophic FactorCell Line, TumorCoumaric AcidsDactinomycinHydrogen PeroxideMicroRNAsNeuroprotective AgentsOxidative StressPC12 CellsPheochromocytomaPhosphorylationProtective AgentsAntioxidantsBrain-Derived Neurotrophic FactorCoumaric AcidsDactinomycinferulic acidHydrogen PeroxideMicroRNAsNeuroprotective AgentsProtective AgentsReactive Oxygen Speciesapoptosiscell signalingferulic acidoxidative stress

Identifiers

PMID33379243
PMCPMC7795901
OpenAlexW3113486220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.