Evidence map›Paper›PMID 33379172›Full record

ArticleChildren (Basel, Switzerland)2020

Idiopathic Hypertrophic Pachymeningitis: Does Earlier Treatment Improve Outcome?

Emilia Rizzo, Ailsa Elizabeth Ritchie, Vinay Shivamurthy, Ata Siddiqui, Ming Lim

Open access · goldAbstract readCase Reports
In one paragraph

Article in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Emilia RizzoFaculty of Medicine and Surgery, University of Catania, Piazza dell'Università 2, 95124 Catania, Italy.
Ailsa Elizabeth RitchiePaediatric Ophthalmology, Evelina London Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Vinay ShivamurthyPaediatric Rheumatology, Evelina London Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Ata SiddiquiDepartment of Neuroradiology, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Ming LimChildren's Neurosciences, Evelina London Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, King's Health Partners Academic Health Science Centre, London SE1 7RS, UK.
Evelina London Children's Healthcare · GBGuy's and St Thomas' NHS Foundation Trust · GBKing's College Hospital NHS Foundation Trust · GBUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/goal: Hypertrophic pachymeningitis is a rare chronic inflammatory disorder characterized by marked fibrous thickening of the cerebral and/or spinal dura mater. This condition has largely been reported in adults, but there are very few reports in children.

methodsWe describe a 14-year-old boy with idiopathic hypertrophic pachymeningitis, who presented with deteriorating vision on a background of severe headache. We evaluated pediatric cases of hypertrophic pachymeningitis and compared treatments and their relation to outcomes.

resultsThere are only eleven pediatric cases of hypertrophic pachymeningitis reported in the literature. In the patients treated with steroids either at presentation or subsequent relapses, a good response was reported. In the cases with delayed initiation of steroid treatment, this was often related to an incomplete recovery. In our patient, this delay may have contributed to his poor visual outcome.

conclusionsEarly initiation of steroid treatment in children with idiopathic hypertrophic pachymeningitis may improve outcomes.

Indexed as

cranial neuropathydural thickeningimmunotherapysarcoidsteroidsvisual failure

Identifiers

PMID33379172
PMCPMC7823752
OpenAlexW3117654112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.