Evidence map›Paper›PMID 33378865›Full record

ArticleMathematical biosciences and engineering : MBE2020

Generating patient-specific virtual tumor populations with reaction-diffusion models and molecular imaging data.

Nick Henscheid

Abstract read
In one paragraph

Article in Mathematical biosciences and engineering : MBE, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Nick HenscheidDepartment of Medical Imaging, University of Arizona, 1501 N. Campbell, Tucson, AZ 85724, USA.

Funding

SPECT Imaging and Parallel ComputingR01EB000803 · NIBIB · UNIVERSITY OF ARIZONA · PI CAUCCI, LUCA · 2012 to 2020
$4.2M
NIBIB NIH HHS R01 EB000803
6 · The paper itself

Abstract

The use of mathematical tumor growth models coupled to noisy imaging data has been suggested as a possible component in the push towards precision medicine. We discuss the generation of population and patient-specific virtual populations in this context, providing in silico experiments to demonstrate how intra- and inter-patient heterogeneity can be estimated by applying rigorous statistical procedures to noisy molecular imaging data, and how the noise properties of such data can be analyzed to estimate uncertainties in predicted patient outcomes.

Indexed as

Models, BiologicalNeoplasmsComputer SimulationHumansMolecular ImagingPrecision Medicineemission computed tomographymathematical onoclogymolecular imagingprecision medicinevirtual clinical trialsvirtual populations

Identifiers

PMID33378865
PMCPMC7780222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.