ReviewTrends in neurosciences2021
Neural Circuits of Interoception.
Review in Trends in neurosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
192 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- The bodily self in fibromyalgia: A systematic review and meta-analysis of body image, body representation, and interoceptive dysfunction.Psychiatry and clinical neurosciences · 2026Pooled it
- Neural correlates of negative aesthetic evaluations in visual art: a neuroimaging meta-analysis.Cerebral cortex (New York, N.Y. : 1991) · 2025Pooled it
- Neuroimaging Meta-Analyses Reveal Convergence of Interoception, Emotion, and Social Cognition Across Neurodegenerative Diseases.Biological psychiatry · 2025Pooled it
- Diminished Interoceptive Accuracy in Attention-Deficit/Hyperactivity Disorder: A Systematic Review.Psychophysiology · 2025Pooled it
- Coactivation of Autonomic and Central Nervous Systems During Processing of Socially Relevant Information in Autism Spectrum Disorder: A Systematic Review.Neuropsychology review · 2024Pooled it
- Psychological interventions for interoception in mental health disorders: A systematic review of randomized-controlled trials.Psychiatry and clinical neurosciences · 2023Pooled it
- Overlapping and specific neural correlates for empathizing, affective mentalizing, and cognitive mentalizing: A coordinate-based meta-analytic study.Human brain mapping · 2021Pooled it
- Effects of a Footbathing Intervention on Physiological, Endocrine, and Psychological Status in Japanese University Students: A Randomized Controlled Trial.International journal of environmental research and public health · 2024Trial
- Heartbeat-evoked neural response abnormalities in generalized anxiety disorder during peripheral adrenergic stimulation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Trial
- Region- and time- specific effects of ketamine on cerebral blood flow: a randomized controlled trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Trial
- Impact of ibuprofen and peroxisome proliferator-activated receptor gamma on emotion-related neural activation: A randomized, placebo-controlled trial.Brain, behavior, and immunity · 2021Trial
- The Interaction Between the Central Nervous System and Dental Tissues: Hypothetical Dental Interoception Inferred From Skeletal Interoception.Journal of oral rehabilitation · 2026Review
- Whole-brain, all-optical interrogation of neuronal dynamics underlying gut and vascular interoception in zebrafish.Nature communications · 2026Article
- The Mind From Within: Visceral Roots of Human Cognition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Longitudinal co-activation pattern analysis of menstrual cycle-related brain dynamics in primary dysmenorrhea.iScience · 2026Article
- Exploring the relationship between interoception and mental body representation in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Human forebrain neural synchronization and entrainment to breathing during wakefulness, sleep, and external mechanical ventilation.Nature communications · 2026Article
- A novel interoceptive subfornical organ to infralimbic cortex mechanism relays airway inflammation effects on fear extinction.Journal of neuroinflammation · 2026Article
- Targeted Magnetic Nanodiscs for Wireless Causal Manipulation of Gut-Brain Circuits.bioRxiv : the preprint server for biology · 2026Article
- Bed nucleus of the stria terminalis connectivity during food cue and taste processing under stress.Nature communications · 2026Article
132 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The present paper considers recent progress in our understanding of the afferent/ascending neural pathways and neural circuits of interoception. Of particular note is the extensive role of rostral neural systems, including cortical systems, in the recognition of internal body states, and the reciprocal role of efferent/descending systems in the regulation of those states. Together these reciprocal interacting networks entail interoceptive circuits that play an important role in a broad range of functions beyond the homeostatic maintenance of physiological steady-states. These include the regulation of behavioral, cognitive, and affective processes across conscious and nonconscious levels of processing. We highlight recent advances and knowledge gaps that are important for accelerating progress in the study of interoception.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.