ArticleJournal of experimental botany2021
Restriction of cytosolic sucrose hydrolysis profoundly alters development, metabolism, and gene expression in Arabidopsis roots.
Article in Journal of experimental botany, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- A conserved hexapeptide switch controls autoinhibition of plant cytosolic invertases.Nature plants · 2026Article
- Regulation of maize root growth by local phosphorus availability, sucrose metabolism, and partitioning.Annals of botany · 2025Article
- Enhanced lignin and cellulose metabolism promote cell wall synthesis and growth of wild soybean HRA under alkali stress.Annals of botany · 2025Article
- Xylem Parenchyma Anatomy and Gene Expression Patterns Indicate Mechanisms of Cavitation Resistance inPlant-environment interactions (Hoboken, N.J.) · 2025Article
- Genome-wide identification of invertase genes in sweetpotato and its response to nitrogen and planting densities.BMC plant biology · 2025Article
- CINV1 and CINV2 are required for increased tolerance to diverse stresses after ethylene-pretreatment of germinating seeds.PloS one · 2025Article
- Exploring the role of GhN/AINV23: implications for plant growth, development, and drought tolerance.Biology direct · 2024Article
- Circadian regulation of metabolism across photosynthetic organisms.The Plant journal : for cell and molecular biology · 2023Review
- The class VIII myosin ATM1 is required for root apical meristem function.Development (Cambridge, England) · 2023Article
- Genome-Wide Identification and Expression Patterns of Cucumber Invertases and Their Inhibitor Genes.International journal of molecular sciences · 2023Article
- Ethylene-mediated metabolic priming increases photosynthesis and metabolism to enhance plant growth and stress tolerance.PNAS nexus · 2023Article
- How pollen tubes fight for food: the impact of sucrose carriers and invertases ofFrontiers in plant science · 2023Article
- Highest Defoliation Tolerance inFrontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Plant roots depend on sucrose imported from leaves as the substrate for metabolism and growth. Sucrose and hexoses derived from it are also signalling molecules that modulate growth and development, but the importance for signalling of endogenous changes in sugar levels is poorly understood. We report that reduced activity of cytosolic invertase, which converts sucrose to hexoses, leads to pronounced metabolic, growth, and developmental defects in roots of Arabidopsis (Arabidopsis thaliana) seedlings. In addition to altered sugar and downstream metabolite levels, roots of cinv1 cinv2 mutants have reduced elongation rates, cell and meristem size, abnormal meristematic cell division patterns, and altered expression of thousands of genes of diverse functions. Provision of exogenous glucose to mutant roots repairs relatively few of the defects. The extensive transcriptional differences between mutant and wild-type roots have hallmarks of both high sucrose and low hexose signalling. We conclude that the mutant phenotype reflects both low carbon availability for metabolism and growth and complex sugar signals derived from elevated sucrose and depressed hexose levels in the cytosol of mutant roots. Such reciprocal changes in endogenous sucrose and hexose levels potentially provide rich information about sugar status that translates into flexible adjustments of growth and development.
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