Evidence map›Paper›PMID 33378092›Full record

ArticleMedical physics2021

Application of radiochromic gel dosimetry to commissioning of a megavoltage research linear accelerator for small-field animal irradiation studies.

Noora Ba Sunbul, Ibrahim Oraiqat, Benjamin Rosen, Cameron Miller, Christopher Meert, Martha M Matuszak, Shaun Clarke, Sara Pozzi, Jean M Moran, Issam El Naqa

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Advancements in Tissue-Equivalent Gel Dosimeters.Gels (Basel, Switzerland) · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Noora Ba SunbulDepartment of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.
Ibrahim OraiqatDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Benjamin RosenDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Cameron MillerDepartment of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.
Christopher MeertDepartment of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.
Martha M MatuszakDepartment of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.
Shaun ClarkeDepartment of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.
Sara PozziDepartment of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI, USA.
Jean M MoranDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Issam El NaqaDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
University of Michigan–Ann Arbor · USMoffitt Cancer Center · US

Funding

Combined radiation acoustics and ultrasound imaging for real-time guidance in radiotherapyR37CA222215 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EL NAQA, ISSAM M. · 2018 to 2024
$3.5M
Academic Research Initiative 2016-DN-077-ARI106Hadramout Establishment for Human DevelopmentNCI NIH HHS R37 CA222215NIH HHS R37CA222215
6 · The paper itself

Abstract

purposeTo develop and implement an efficient and accurate commissioning procedure for small-field static beam animal irradiation studies on an MV research linear accelerator (Linatron-M9) using radiochromic gel dosimetry. MATERIALS: The research linear accelerator (Linatron-M9) is a 9 MV linac with a static fixed collimator opening of 5.08 cm diameter. Lead collimators were manually placed to create smaller fields of 2 × 2 cm

resultsAbsolute dosimetry measurements were confirmed within 1.4% (k = 2, 95% confidence = 5%). The relative output factor of the small fields measured with films and gels agreed with a maximum relative percent error difference between the two methods of 1.1 % for the 1 × 1 cm

conclusionThis work provides a commissioning process to measure the beam characteristics of a fixed beam MV accelerator with detailed dosimetric evaluation for its implementation in megavoltage small animal irradiation studies. Radiochromic gel dosimeters are efficient small-field relative dosimetry tools providing 3D dose measurements allowing for full representation of dose, dosimeter misalignment corrections and high reproducibility with low inter-dosimeter variability. Overall, radiochromic gels are valuable for fast, full relative dosimetry commissioning in comparison to films for application in high-energy small-field animal irradiation studies.

Indexed as

Particle AcceleratorsRadiometryAnimalsFilm DosimetryRadiation DosimetersRadiotherapy, High-EnergyReproducibility of Resultsanimal irradiator and small-field dosimetrycommissioninggel dosimetry

Identifiers

PMID33378092
PMCPMC8917956
OpenAlexW3116340118

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.