Evidence map›Paper›PMID 33377911›Full record

ArticleGigaScience2020

GALLO: An R package for genomic annotation and integration of multiple data sources in livestock for positional candidate loci.

Pablo A S Fonseca, Aroa Suárez-Vega, Gabriele Marras, Ángela Cánovas

Open access · goldAbstract read
In one paragraph

Article in GigaScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed, 4 pooled it
24.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 4 syntheses or guidelines pooled it, 307 citations in OpenAlex.

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103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Pablo A S FonsecaUniversity of Guelph, Department of Animal Biosciences, Centre for Genetic Improvement of Livestock, 50 Stone Rd E, Guelph N1G 2W1, ONT, Canada.
Aroa Suárez-VegaUniversity of Guelph, Department of Animal Biosciences, Centre for Genetic Improvement of Livestock, 50 Stone Rd E, Guelph N1G 2W1, ONT, Canada.
Gabriele MarrasUniversity of Guelph, Department of Animal Biosciences, Centre for Genetic Improvement of Livestock, 50 Stone Rd E, Guelph N1G 2W1, ONT, Canada.
Ángela CánovasUniversity of Guelph, Department of Animal Biosciences, Centre for Genetic Improvement of Livestock, 50 Stone Rd E, Guelph N1G 2W1, ONT, Canada.
University of Guelph · CADigital Research Alliance of Canada

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe development of high-throughput sequencing and genotyping methodologies has enabled the identification of thousands of genomic regions associated with several complex traits. The integration of multiple sources of biological information is a crucial step required to better understand patterns regulating the development of these traits.

findingsGenomic Annotation in Livestock for positional candidate LOci (GALLO) is an R package developed for the accurate annotation of genes and quantitative trait loci (QTLs) located in regions identified in common genomic analyses performed in livestock, such as genome-wide association studies and transcriptomics using RNA sequencing. Moreover, GALLO allows the graphical visualization of gene and QTL annotation results, data comparison among different grouping factors (e.g., methods, breeds, tissues, statistical models, studies), and QTL enrichment in different livestock species such as cattle, pigs, sheep, and chickens.

conclusionsConsequently, GALLO is a useful package for annotation, identification of hidden patterns across datasets, and data mining previously reported associations, as well as the efficient examination of the genetic architecture of complex traits in livestock.

Indexed as

Genome-Wide Association StudyLivestockAnimalsCattleChickensGenomicsInformation Storage and RetrievalPolymorphism, Single NucleotideQuantitative Trait LociSheepSwinedata mininggene annotationlivestockmulti-omics integrationQTL annotationQTL enrichment analysis

Identifiers

PMID33377911
PMCPMC7772745
OpenAlexW3116451876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.