Evidence map›Paper›PMID 33377870›Full record

ArticleeLife2020

Tissue-autonomous immune response regulates stress signaling during hypertrophy.

Robert Krautz, Dilan Khalili, Ulrich Theopold

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Robert Krautz *Department of Molecular Biosciences, The Wenner-Gren Institute (MBW), Stockholm University, Stockholm, Sweden.ORCID 0000-0003-0457-1348
Dilan Khalili *Department of Molecular Biosciences, The Wenner-Gren Institute (MBW), Stockholm University, Stockholm, Sweden.ORCID 0000-0002-9785-9641
Ulrich TheopoldDepartment of Molecular Biosciences, The Wenner-Gren Institute (MBW), Stockholm University, Stockholm, Sweden.ORCID 0000-0002-1009-8254
Stockholm University · SE

Funding

Swedish Cancer Foundation CAN 2010/553Swedish Cancer Foundation CAN 2013/546Vetenskapsrådet VR-2010-5988Vetenskapsrådet VR 2016-04077
6 · The paper itself

Abstract

Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway via

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsGene Expression Regulation, DevelopmentalHypertrophyIMP DehydrogenaseLarvaMAP Kinase Signaling SystemSignal TransductionStress, PhysiologicalDrosophila ProteinsDRS protein, DrosophilaIMP Dehydrogenaseras protein, Drosophilacancer biologyD. melanogasterdorsalDrosomycinhypertrophyimmunologyinflammationinnate immunityJNKsalivary gland

Identifiers

PMID33377870
PMCPMC7880693
OpenAlexW3113395967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.