Evidence map›Paper›PMID 33377136›Full record

ArticleCancer medicine journal2020

Burden of Proof: Evaluating the Efficacy of Tumor Mutational Burden (TMB) in Predicting Response to Immune Checkpoint Inhibitors.

James Newman, Nagashree Seetharamu, Muhammad Wasif Saif

Abstract read
In one paragraph

Article in Cancer medicine journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James NewmanNorthwell Health Cancer Institute, Lake Success, NY, USA.
Nagashree SeetharamuNorthwell Health Cancer Institute, Lake Success, NY, USA.
Muhammad Wasif SaifNorthwell Health Cancer Institute, Lake Success, NY, USA.

Funding

Northwell Health NCORPUG1CA189850 · NCI · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI VINCENT P VINCIGUERRA · 2014 to 2026
$13.3M
NCI NIH HHS UG1 CA189850
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CancerImmune checkpoint inhibitors (ICIs)Microsatellite instability-high (MSI-H)Microsatellite stable (MSS)POLD1POLETumor mutational burden (TMB)

Identifiers

PMID33377136
PMCPMC7769129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.