Evidence map›Paper›PMID 33377127›Full record

ArticleCell reports. Medicine2020

Delivery Mode Affects Stability of Early Infant Gut Microbiota.

Caroline M Mitchell, Chiara Mazzoni, Larson Hogstrom, Allison Bryant, Agnes Bergerat, Avital Cher, Shawna Pochan, Penelope Herman, Maureen Carrigan, Karen Sharp and 5 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports. Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06282952 (Section-Born Infants and SUccessful Health Outcomes After Fecal Microbiota Transplantation), which is not on this map. Cited by 166 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
166citing papers in PubMed, 7 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06282952 narecruitingnot on this mapstarted 2026, after this paper: background citation

Section-Born Infants and SUccessful Health Outcomes After Fecal Microbiota Transplantation (SISU-FMT)

TypeinterventionalSponsorOulu University HospitalRan2026 to 2036Enrolled460ConditionsFecal Microbiota Transplantation, Cesarean Section, Overweight and ObesityArmsDonor-derived fecal microbiota transplantation
3 · Its place in the literature

Who cites it

166 citing papers in PubMed, 7 syntheses or guidelines pooled it, 224 citations in OpenAlex.

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106 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Caroline M MitchellVincent Obstetrics & Gynecology Department, Massachusetts General Hospital, Boston, MA 02114, USA.
Chiara MazzoniFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91121, Israel.
Larson HogstromBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Allison BryantVincent Obstetrics & Gynecology Department, Massachusetts General Hospital, Boston, MA 02114, USA.
Agnes BergeratVincent Obstetrics & Gynecology Department, Massachusetts General Hospital, Boston, MA 02114, USA.
Avital CherFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91121, Israel.
Shawna PochanVincent Obstetrics & Gynecology Department, Massachusetts General Hospital, Boston, MA 02114, USA.
Penelope HermanVincent Obstetrics & Gynecology Department, Massachusetts General Hospital, Boston, MA 02114, USA.
Maureen CarriganVincent Obstetrics & Gynecology Department, Massachusetts General Hospital, Boston, MA 02114, USA.
Karen SharpVincent Obstetrics & Gynecology Department, Massachusetts General Hospital, Boston, MA 02114, USA.
Curtis HuttenhowerBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Eric S LanderBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Hera VlamakisBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Ramnik J XavierBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Moran YassourFaculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91121, Israel.
Massachusetts General Hospital · USBroad Institute · USHebrew University of Jerusalem · IL

Funding

Large Scale Sequencing and Analysis of GenomesU54HG003067 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GABRIEL, STACEY, LANDER, ERIC S · 2004 to 2015
$568.6M
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 1991 to 2026
$35.3M
Autophagy genes and the microbiome in Crohn's DiseaseR01DK092405 · NIDDK · BROAD INSTITUTE, INC. · PI XAVIER, RAMNIK J · 2012 to 2014
$2.0M
Natural history of the infant gut microbiome in health and disease: establishment, feeding & implications for allergyK99DK113224 · NIDDK · BROAD INSTITUTE, INC. · PI YASSOUR, MORAN · 2017 to 2018
$180k
NHGRI NIH HHS U54 HG003067NIDDK NIH HHS K99 DK113224NIDDK NIH HHS P30 DK043351NIDDK NIH HHS R01 DK092405
6 · The paper itself

Abstract

Mode of delivery strongly influences the early infant gut microbiome. Children born by cesarean section (C-section) lack

Indexed as

Infectious Disease Transmission, VerticalBacteroidesCesarean SectionDelivery, ObstetricFemaleGastrointestinal MicrobiomeHumansInfantMicrobiotaPregnancyinfant gut microbiota, caesarean delivery, Bacteroides, delivery mode, transmission of maternal strains

Identifiers

PMID33377127
PMCPMC7762768
OpenAlexW3116220988

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.