Evidence map›Paper›PMID 33376734›Full record

ReviewBioMed research international2020

Immunological Aspects of Dental Implant Rejection.

Milad Baseri, Faraz Radmand, Reyhaneh Hamedi, Mehdi Yousefi, Hossein Samadi Kafil

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05675241 (Characterizing the Inflammation Around Dental Implants), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05675241 unknown statusnot on this mapstarted 2022, after this paper: background citation

Characterizing the Inflammation Around Dental Implants: Bacterial Infection, Hypersensitivity, or Both?

TypeobservationalSponsorMcGill UniversityRan2022 to 2024Enrolled177ConditionsPeri-Implantitis, Peri-implant Mucositis, Implant Site Reaction, Implant Site InfectionArmsClinical examination of a dental implant, Radiological Examination, Peri-implant crevicular fluid sample collection
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.

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  12. Advancing oral immunology for improving oral health.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Milad Baseri *Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0001-8531-8699
Faraz Radmand *Biotechnology Research Center, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-9761-5663
Reyhaneh HamediDental School, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-4260-8976
Mehdi YousefiResearch Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0003-0099-6728
Hossein Samadi KafilDrug Applied Research Center, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0001-6026-8795
Tabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nowadays, dental implants are a prominent therapeutic approach among dentists for replacing missing teeth. Failure in dental implants is a severe challenge recently. The factors which lead to dental implant failure are known. These factors can be categorized into different groups. In this article, we discussed the immunological aspects of implant failure as one of these groups. Cytokines and immune cells have extensive and various functions in peri-implantitis. The equilibrium between pro and anti-inflammatory cytokines and cells, which involve in this orchestra, has a crucial role in implant prognosis. In conclusion, immune cells, especially macrophages and dendritic cells, almost increased in the patients with implant failure. Also, proinflammatory cytokines were proposed as diagnostic factors according to their higher levels in dental implant rejection.

Indexed as

Anti-Inflammatory AgentsCytokinesDendritic CellsDental ImplantsHumansHypersensitivityImmunity, HumoralInflammationMacrophagesOsseointegrationPeri-ImplantitisPrognosisTitaniumAnti-Inflammatory AgentsCytokinesDental ImplantsTitanium

Identifiers

PMID33376734
PMCPMC7744195
OpenAlexW3111245959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.