Evidence map›Paper›PMID 33376687›Full record

ArticleInternational journal of critical illness and injury science2020

Hemostatic derangement in leptospirosis: A prospective cross-sectional study.

Rasa Threeswaran, Nipun Lakshitha De Silva, Lallindra Gooneratne, Roopen Arya, Shiroma M Handunnetti, Senaka Rajapakse

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of critical illness and injury science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Atypical Cases of Leptospirosis: Insights From Georgia.Case reports in infectious diseases · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Rasa ThreeswaranDepartment of Immunology, Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Colombo, Sri Lanka.
Nipun Lakshitha De SilvaDepartment of Clinical Medicine, Faculty of Medicine, General Sir John Kotelawala Defence University, Colombo, Sri Lanka.
Lallindra GooneratneDepartment of Pathology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Roopen AryaKing's Thrombosis Center, King's College Hospital, London, England, UK.
Shiroma M HandunnettiDepartment of Immunology, Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Colombo, Sri Lanka.
Senaka RajapakseDepartment of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
University of Colombo · LKGeneral Sir John Kotelawala Defence University · LKKing's College Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextCoagulation abnormalities have been observed among leptospirosis patients. However, coagulopathy in severe leptospirosis has not been further characterized.

aimsThe aim of this study was to evaluate conventional coagulation and rotational thromboelastometry (ROTEM SETTINGS AND

designThis prospective cross-sectional comparative study included patients presenting to a tertiary hospital in Sri Lanka with clinically and serologically confirmed leptospirosis (14 severe and 6 mild), dengue (6), sepsis (5), and 6 healthy individuals. SUBJECTS AND

methodsBlood samples were collected between the 3 STATISTICAL ANALYSIS USED: ANOVA

resultsPT and aPTT were prolonged in leptospirosis patients and were corrected with normal plasma. TT was not significantly prolonged in leptospirosis. Fibrinogen was significantly elevated in severe leptospirosis (

conclusionsAbnormalities in conventional coagulation parameters occur in leptospirosis. However, ROTEM parameters in leptospirosis are not significantly altered.

Indexed as

Coagulationhemorrhageleptospirosisthromboelastography

Identifiers

PMID33376687
PMCPMC7759069
OpenAlexW3093401599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.