Evidence map›Paper›PMID 33376577›Full record

ArticleOxidative medicine and cellular longevity2020

A Positive Feed Forward Loop between Wnt/

Jia Ma, Qian Cai, Dandan Yang, Jiali Yang, Jing Xue, Miao Yu, Yingxue Liu, Fucheng Ma, Feng Li, Xiaoming Liu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Silicosis: from pathogenesis to therapeutics.Frontiers in pharmacology · 2025
    Review
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Jia MaKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, College of Life Science, Ningxia University, Yinchuan, Ningxia 750021, China.
Qian CaiKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, College of Life Science, Ningxia University, Yinchuan, Ningxia 750021, China.
Dandan YangKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, College of Life Science, Ningxia University, Yinchuan, Ningxia 750021, China.
Jiali YangKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, College of Life Science, Ningxia University, Yinchuan, Ningxia 750021, China.
Jing XueGeneral Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China.
Miao YuKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, College of Life Science, Ningxia University, Yinchuan, Ningxia 750021, China.
Yingxue LiuKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, College of Life Science, Ningxia University, Yinchuan, Ningxia 750021, China.
Fucheng MaKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, College of Life Science, Ningxia University, Yinchuan, Ningxia 750021, China.
Feng LiGeneral Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China.ORCID https://orcid.org/0000-0002-7991-8011
Xiaoming LiuKey Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in the Western, College of Life Science, Ningxia University, Yinchuan, Ningxia 750021, China.ORCID https://orcid.org/0000-0002-3902-9105
Ningxia University · CNNingxia Medical University · CNUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silicosis is a chronic fibrotic lung disease caused by the accumulation of silica dust in the distal lung. Canonical Wnt signaling and NADPH oxidase 4 (NOX4) have been demonstrated to play a crucial role in the pathogenesis of pulmonary fibrosis including silicosis. However, the underlying mechanisms of crosstalk between these two signalings are not fully understood. In the present study, we aimed to explore the interaction of Wnt/

Indexed as

AnimalsEpithelial CellsEpithelial-Mesenchymal TransitionFemaleLungMaleMiceNADPH Oxidase 4Respiratory MucosaSilicon DioxideSilicosisWnt Signaling PathwayNADPH Oxidase 4Nox4 protein, mouseSilicon Dioxide

Identifiers

PMID33376577
PMCPMC7744200
OpenAlexW3111410363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.