Evidence map›Paper›PMID 33376381›Full record

ArticleJournal of inflammation research2020

Inflammatory Subtypes in Classic Asthma and Cough Variant Asthma.

Jie Gao, Feng Wu, Sifang Wu, Xing Yang

Open access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cough-Variant Asthma: A Review of Clinical Characteristics, Diagnosis, and Pathophysiology.The journal of allergy and clinical immunology. In practice · 2025
    Review
  5. Cough-Variant Asthma: The Asthma Phenotype No One Coughs About.American journal of respiratory cell and molecular biology · 2025
    Article
  6. Observational
  7. Article
  8. Review
  9. Asthma Phenotypes in the Era of Personalized Medicine.Journal of clinical medicine · 2023
    Review
  10. Cough hypersensitivity and chronic cough.Nature reviews. Disease primers · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Phenotypes and endotypes of cough in asthma.Therapeutic advances in respiratory disease
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jie GaoDepartment of Pulmonary and Critical Care Medicine, Huizhou the Third People's Hospital, Guangzhou Medical College, Huizhou 516002, People's Republic of China.ORCID 0000-0002-8223-5377
Feng WuDepartment of Pulmonary and Critical Care Medicine, Huizhou the Third People's Hospital, Guangzhou Medical College, Huizhou 516002, People's Republic of China.ORCID 0000-0002-6911-4896
Sifang WuDepartment of Pulmonary and Critical Care Medicine, Huizhou the Third People's Hospital, Guangzhou Medical College, Huizhou 516002, People's Republic of China.
Xing YangDepartment of Pulmonary and Critical Care Medicine, Huizhou the Third People's Hospital, Guangzhou Medical College, Huizhou 516002, People's Republic of China.
Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMeasurement of sputum is used to define airway inflammatory phenotypes. Cough variant asthma (CVA) is considered to be the initial stage of classic asthma (CA). The aim of this study was to describe the association between the different subtypes of CVA and CA.

methodsA total of 459 patients with CVA and CA were screened for the study. All included patients performed spirometry, underwent a bronchial challenge with methacholine and induced sputum according to the guidelines.

resultsA higher frequency of female patients were found with CVA and the eosinophilic airway inflammation of CVA than in CA and the noneosinophilic airway inflammation of CA (

conclusionEosinophilia may be associated with more severe disease, yet there was no difference in spirometry between the eosinophilic and noneosinophilic groups, and the BHR difference was not dramatic.

Indexed as

airway inflammatory typesbronchial hyper-responsivenesscough variant asthmasputum induction

Identifiers

PMID33376381
PMCPMC7765682
OpenAlexW3118057427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.