Evidence map›Paper›PMID 33376283›Full record

ReviewInternational journal of trichology

Effect of Oral Minoxidil for Alopecia: Systematic Review.

Israel Junior Borges do Nascimento, Matthew Harries, Vanessa Barreto Rocha, Jacqueline Y Thompson, Chun Hoong Wong, Hamed Kord Varkaneh, Nathália Sernizon Guimarães, Alair Junior Rocha Arantes, Milena Soriano Marcolino

Abstract readReview
In one paragraph

Review in International journal of trichology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Menopause, skin and common dermatoses. Part 1: hair disorders.Clinical and experimental dermatology · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Effects of taxifolin from enzymatic hydrolysis ofFrontiers in bioengineering and biotechnology · 2022
    Article
  9. Pharmacological Management of Pattern Hair Loss.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Israel Junior Borges do NascimentoDepartment of Internal Medicine, University Hospital and School of Medicine, Federal University of Minas Gerais, Brazil.
Matthew HarriesThe Dermatology Centre, University of Manchester, Salford Royal NHS Foundation Trust, Salford, UK.
Vanessa Barreto RochaDepartment of Dermatology, University Hospital, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Jacqueline Y ThompsonInstitute of Inflammation and Ageing, University of Birmingham, Birmingham, England, UK.
Chun Hoong WongDepartment of Pharmacy, Serdang Hospital, Kajang, Selangor, Malaysia.
Hamed Kord VarkanehStudent Research Commitee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nathália Sernizon GuimarãesDepartment of Nutrition, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, Brazil.
Alair Junior Rocha ArantesDepartment of Internal Medicine, University Hospital and School of Medicine, Federal University of Minas Gerais, Brazil.
Milena Soriano MarcolinoDepartment of Internal Medicine, University Hospital and School of Medicine, Federal University of Minas Gerais, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with major presentations of alopecia experience physically harmful effects and psychological comorbidities, such as depression and anxiety. Oral minoxidil (OM) has been suggested by dermatologists as a potential remedy; however, its effectiveness remains unclear. This systematic review aims to collate published studies and to analyze the effect of OM among patients diagnosed with any type of alopecia. For this systematic review, Medline/PubMed, Cochrane Central, EMBASE, Web of Sciences, and Latin American and Caribbean Health Sciences Information System were searched for relevant studies from inception to September 21, 2019. Of 1960 studies retrieved in several electronic databases and three additional records identified though reference list from potentially eligible studies, nine studies (one randomized controlled trial and eight nonrandomized controlled trials) met the requirements and were used in our analysis. Although we found positive effects in favor of OM, this should be interpreted cautiously due to very low quality of the evidence of outcomes in the selected studies. Definitive conclusions are not possible without high-quality trials. This review has highlighted the absence of high-quality randomized controlled trials evaluating OM in the treatment of various types of alopecia. Given the mild adverse events of OM, future studies should also analyze doses and duration to maximize efficacy and decrease side effects.

Indexed as

Alopeciaevidence-based medicineminoxidilsystematic review

Identifiers

PMID33376283
PMCPMC7759057

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.